PPISURV statistics

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Associated diseases

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PPISURV specifications

Information


Unique identifier OMICS_12519
Name PPISURV
Interface Web user interface
Restrictions to use None
Input data PPISURV accepts as input a wide spectrum of gene identifiers (Entrez Gene Id, GeneSymbol, UniProt/Swiss-Prot, UniGene, Ensembl, RefSeqIDs).
Computer skills Basic
Stability Stable
Maintained Yes

Maintainer


  • person_outline Alexey V. Antonov <>

Publication for PPISURV

PPISURV in publications

 (8)
PMCID: 5944004
PMID: 29743122
DOI: 10.1186/s13046-018-0748-9

[…] and classified as non-responders [] displayed marginally higher spin1 expression than those classified as responders (fig. , p = 0.0655). the prognostic role of spin1 was determined by the ppisurv (http://www.chemoprofiling.org/cgi-bin/geo/cancertarget/web_run_ct.v0.s1.pl) database [, ]. the results showed that patients with high expression of spin1 (n = 230) had poorer survival […]

PMCID: 5726622
PMID: 29249894
DOI: 10.1177/1179066017731564

[…]  minutes at 37°c in the dark. in total, 10 000 events were recorded for each sample using the becton dickinson facscanto ii and facsdiva 6.0 software (becton dickinson) for acquisition and analysis., ppisurv was used to correlate survival rates in patients with cancer to the expression level of syk. in each data set, samples were grouped with respect to expression rank of the gene, which reflects […]

PMCID: 5352040
PMID: 27901477
DOI: 10.18632/oncotarget.13585

[…] patient identity and data privacy was protected. furthermore, we used several sera from the study performed by raja et al. 2007 []., we used a free online datamining tool (http://www.bioprofiling.de/ppisurv). ppisurv automatically correlates expression of an input gene interactome with survival rates on > 40 publicly available clinical expression data sets covering various tumors involving […]

PMCID: 4855670
PMID: 27054339
DOI: 10.1038/cddis.2016.91

[…] of translational relevance of ank1 have been performed with the bioprofiling.de online datamining tools using publically available clinical gene expression data from the geo omnibus repository. the ppisurv tool was used to correlate gene expression data with cancer patient survival. to demonstrate translational relevance of potential association between ank1 and dna damage genes we used […]

PMCID: 4712512
PMID: 26763900
DOI: 10.1186/s12864-015-2260-3

[…] the cytoscape software tool []. all statistical calculations, nca and clustering were done in matlab, mathworks., we conducted survival analysis of mirnas and tfs using the tools ‘mirumir’ [] and ‘ppisurv’ [] respectively, both developed by antonov av et al. these tools integrate publicly available clinical data such as the geo repository. briefly, these tools utilize the rank information […]


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PPISURV institution(s)
Toxicology Unit, Hodgkin Building, Medical Research Council, Leicester University, Leicester, UK; Molecular Pharmacology Laboratory, Technological University, St-Petersburg, Russia; Institute for Molecular Medicine Finland FIMM, University of Helsinki; Helsinki, Finland; Donnelly Center for Cellular and Biomolecular Research, University of Toronto, Toronto, ON, Canada; Department of Experimental Medicine and Surgery, University of Rome ‘Tor Vergata’, Rome, Italy; Department of Biochemistry, University of Leicester, Leicester, UK; Gene Expression Programme, Institute of Cytology, St-Petersburg, Russia
PPISURV funding source(s)
This work was supported by the UK Medical Research Council (MRC) and funding from Russian Federal grants 14.B37.21.1967, 16.740.11.036 and 11.G34.31.0069.

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