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PredGPI specifications


Unique identifier OMICS_07284
Name PredGPI
Interface Web user interface
Restrictions to use None
Computer skills Basic
Stability Stable
Maintained Yes

Publication for PredGPI

PredGPI citations


Identification and characterization of ORF19.1725, a novel gene contributing to the white cell pheromone response and virulence associated functions in Candida albicans

PMCID: 5955465
PMID: 29726301
DOI: 10.1080/21505594.2018.1456228

[…] / [], and a cleavage site was predicted between the 26th and 27th amino acids ( and ). Although an ω site at the position of the 700th amino acid was predicted by the PredGPI website (, this prediction is less likely to be accurate due to a very low specificity (32.5%) ( and ) []. Interestingly, four tandem repeats were found ( […]


Antibodies to in silico selected GPI anchored Theileria parva proteins neutralize sporozoite infection in vitro

Vet Immunol Immunopathol
PMCID: 5956992
PMID: 29678234
DOI: 10.1016/j.vetimm.2018.03.004

[…] We performed a bioinformatics search of the re-annotated T. parva genome (cited in ) for proteins predicted to contain a C-terminal GPI anchor signal and/or an N-terminal signal peptide using PredGPI () and SignalP 4.1 (), respectively. Following PredGPI analysis, GPI-proteins were sorted based on their Hidden Markov Model (HMM) scores in decreasing order of prediction accuracy, from highl […]


Comparative systems analysis of the secretome of the opportunistic pathogen Aspergillus fumigatus and other Aspergillus species

Sci Rep
PMCID: 5919931
PMID: 29700415
DOI: 10.1038/s41598-018-25016-4

[…] 99.8%, respectively, of TargetP 1.1 to be 95.1% and 98.3%, respectively, and of ProtComp 9 to be 63.3% and 97.2%, respectively. In addition, Pierleoni et al. found the sensitivity and specificity of PredGPI to be 77.2% and 99.9%, respectively, and of big-PI to be 54.5% and 99.7%, respectively. Note that sensitivity measures the fraction of true positive predictions while specificity measures the […]


A Predicted Mannoprotein Participates in Cryptococcus gattii Capsular Structure

PMCID: 5917426
DOI: 10.1128/mSphere.00023-18

[…] y, the presence of a signal peptide, a glycosylphosphatidylinositol (GPI) anchor, and serine-threonine-rich sites that would comprise the glycosylation site (). Employing a combination of SignalP (), PredGPI (), and GlycoEP () analyses, the presence of 34 mannoprotein-coding genes in C. gattii R265 genome was predicted (see  in the supplemental material). Profile assignments employing InterProScan […]


Systemic surfaceome profiling identifies target antigens for immune based therapy in subtypes of advanced prostate cancer

Proc Natl Acad Sci U S A
PMCID: 5949005
PMID: 29686080
DOI: 10.1073/pnas.1802354115

[…] mponents of the Plasma Membrane), putative transmembrane proteins based on analysis of the UniProt proteome of Homo sapiens using TMHMM (Version 2.0) (), and predictions of GPI-anchored proteins from PredGPI (). […]


A Carbohydrate Moiety of Secreted Stage Specific Glycoprotein 4 Participates in Host Cell Invasion by Trypanosoma cruzi Extracellular Amastigotes

Front Microbiol
PMCID: 5903068
PMID: 29692765
DOI: 10.3389/fmicb.2018.00693

[…] n were identified by NetNGlyc 1.0 and NetOGlyc 4.0, respectively. Interproscan v. 4.8 software was used to identify different protein domains. Prediction of GPI-anchoring sites was performed with the PredGPI program. […]

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PredGPI institution(s)
Biocomputing Group, Department of Biology, University of Bologna, Bologna, Italy

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