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PreDisorder specifications

Information


Unique identifier OMICS_03621
Name PreDisorder
Interface Web user interface
Restrictions to use None
Computer skills Basic
Stability Stable
Maintained Yes

Publication for PreDisorder

PreDisorder citations

 (10)
library_books

Systematic discovery of novel eukaryotic transcriptional regulators using sequence homology independent prediction

2017
BMC Genomics
PMCID: 5485742
PMID: 28651538
DOI: 10.1186/s12864-017-3853-9

[…] east based on experimental evidence (autoactivation). The subcellular localization of Arabidopsis proteins was predicted using YLoc []. The disordered amino acids in each protein were predicted using Predisorder 1.1 []. We calculated the ratio of disordered residues for each protein as the number of disordered amino acids divided by the protein length. Predisorder does not work for proteins larger […]

call_split

Evidence supporting a critical contribution of intrinsically disordered regions to the biochemical behavior of full length human HP1γ

2015
J Mol Model
PMCID: 4683166
PMID: 26680990
DOI: 10.1007/s00894-015-2874-z
call_split See protocol

[…] egions as well as the HP1γ linker (Ala82 – Arg115), we used a meta-prediction approach that integrated the data from PrDOS [], metaPrDOS [], POODLE [], DISpro [], DisEMBL [], IUPred [], PONDR-FIT [], PreDisorder [], OnD-CRF [], RONN [], FoldIndex [], DISOclust [], and GlobPlot2 []. As a negative control, we subjected the sequence of an ordered alpha helix from HP1γ (PQIVIAFYEER; residues 161–171) […]

call_split

An Overview of Predictors for Intrinsically Disordered Proteins over 2010–2014

2015
Int J Mol Sci
PMCID: 4632708
PMID: 26426014
DOI: 10.3390/ijms161023446
call_split See protocol

[…] ghtly different manner []. It is the first time to predict disorder proteins using such method. The dataset used for training is from 723 proteins originally used for the development of DISpro [] and PreDisorder []. Those proteins are more than 30 residues in length, and comprised of 13909 disordered residues (about 6.5% disordered). In addition, DNdisorder also utilized the dataset from CASP9 and […]

library_books

The Structural Characterization of Tumor Fusion Genes and Proteins

2015
PMCID: 4546970
PMID: 26347798
DOI: 10.1155/2015/912742

[…] rediction []. A residue locating inside a disorder region was defined as beholding a disorder score larger than 0.5. To validate the prediction of IUPred, other prediction pieces of software, such as PreDisorder [] and PONDR [–], were also used to predict the structure of the 108 fusion proteins. […]

call_split

An Overview of Practical Applications of Protein Disorder Prediction and Drive for Faster, More Accurate Predictions

2015
Int J Mol Sci
PMCID: 4519904
PMID: 26198229
DOI: 10.3390/ijms160715384
call_split See protocol

[…] at least 30 residues long, and residues missing from the experimentally-determined structure were considered disordered. This dataset was initially used to develop DISpro [] and later used to produce PreDisorder [] and DNdisorder []. The DisProt dataset is a set of proteins that contain regions that have been experimentally determined to be ordered or disordered []. For this work, Version 6.0 was […]

call_split

An integrated map of HIV genome wide variation from a population perspective

2015
Retrovirology
PMCID: 4358901
PMID: 25808207
DOI: 10.1186/s12977-015-0148-6
call_split See protocol

[…] en structurally unstable without their partner molecules []. We estimated the intrinsically disordered structures of HIV-1 subtype B proteins using three software packages: MetaPrDOS [], VSL2P [] and PreDisorder v1.1 []. A disorder score (a numerical value between 0 and 1) of each amino acid position was estimated by 17 methods in these 3 software packages. An amino acid position was estimated as […]

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PreDisorder institution(s)
Department of Computer Science, University of Missouri-Columbia, Columbia, MO, USA

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