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PresCont specifications


Unique identifier OMICS_08138
Name PresCont
Software type Package/Module
Interface Command line interface
Restrictions to use None
Operating system Unix/Linux
Computer skills Advanced
Stability Stable
Maintained Yes


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PresCont citations


Utilizing knowledge base of amino acids structural neighborhoods to predict protein protein interaction sites

PMCID: 5731498
PMID: 29244012
DOI: 10.1186/s12859-017-1921-4

[…] for the planedimers and transcomp1 datasets, surface residues were defined as those with rasa≥0.05 while for ds188 the rule was rasa>0., results showing the comparison of inspire with sppider [], prescont [] and metappisp [] in terms of mcc on the planedimers and transcomp1 datasets are in table . the mcc values of the other methods are taken from []. the comparison with predus [], prise [], […]


Algorithmic approaches to protein protein interaction site prediction

PMCID: 4338852
PMID: 25713596
DOI: 10.1186/s13015-015-0033-9

[…] reduced space, the attribute vectors of the peptides are then used to construct a random forest (rf) classifier [], an ensemble learner based on combining the output of multiple decision trees., the prescont algorithm [] combines local residue features with environmental information as input to an svm. the creators of prescont note their belief that interface prediction will not benefit […]


CRF based models of protein surfaces improve protein protein interaction site predictions

PMCID: 4150965
PMID: 25124108
DOI: 10.1186/1471-2105-15-277

[…] also successfully applicable, if the distributions are only unimodal over a certain sub-domain. the improvement is then restricted to that domain. thus we were able to improve the prediction of the prescont server devised by zellner et al. (2011) on planedimers., our results strongly suggest that pcrfs form a methodological framework to improve residue-wise score-based protein-protein interface […]

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PresCont institution(s)
Institute of Biophysics and Physical Biochemistry, University of Regensburg, Regensburg, Germany

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