Prest-plus statistics

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Associated diseases

Associated diseases

Prest-plus specifications


Unique identifier OMICS_13154
Name Prest-plus
Software type Package/Module
Interface Command line interface
Restrictions to use None
Operating system Unix/Linux, Mac OS
Programming languages C++
Computer skills Advanced
Version 4.09
Stability Stable
Source code URL
Maintained Yes


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  • person_outline Apostolos Dimitromanolakis <>

Publications for Prest-plus

Prest-plus in publications

PMCID: 5586387
PMID: 28739658
DOI: 10.1534/genetics.117.1122

[…] has the highest accuracy across all levels of relatedness, and it accounts for population structure using principal components (pcs) inferred from a set of samples with low relatedness (). however, prest-plus has only slightly lower performance than pc-relate even though it does not account for population structure. prest-plus implements a hidden markov model that enables it to leverage linkage […]

PMCID: 5510992
PMID: 28715588
DOI: 10.1167/iovs.16-21271

[…] sib-pair, and any snp with more than one mendelian error was dropped. plink was used to detect sex discrepancies; samples that did not appear sufficiently matched to their recorded sex were dropped. prest-plus was used to identify duplicate samples. snps with more than one error in blind duplicates or hapmap controls were dropped. heterozygosity rates across samples were checked, and outlier […]

PMCID: 3914019
PMID: 24479562
DOI: 10.1186/1471-2164-15-85

[…] final comparisons were carried out using the 641 samples in common., kinship coefficients for all pairwise individuals were generated from exome chip genotypes and sequence data were estimated using prest-plus v4.09 []., for calculation of the allele frequencies given the pedigree information, initially kininbcoef v1.1 is used to create kinship coefficients from the known pedigree structure […]

PMCID: 3037415
PMID: 21347284
DOI: 10.1371/journal.pgen.1001304

[…] nucleotides. labeled fragments were hybridized to the microarray, washed and detected. genotypes were called using birdseed v1.33 and quality control steps were performed in plink, eigenstrat and prest-plus –. to confirm sample identity, genotype concordance between 24 snps genotyped in all samples both on the microarrays and using sequenom iplex were monitored. dna samples with genotyping […]

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Prest-plus institution(s)
Division of Biostatistics, Dalla Lana School of Public Health, University of Toronto, Toronto, ON, Canada; Department of Statistical Sciences, University of Toronto, Toronto, ON, Canada; Department of Clinical Biochemistry, University Health Network, Toronto, ON, Canada
Prest-plus funding source(s)
Genetic Analysis Workshop is supported by NIH grant R01 GM031575. The research is supported by the Natural Sciences and Engineering Research Council of Canada (NSERC) and the Canadian Institutes of Health Research (CIHR).

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