PreTIS statistics

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Associated diseases

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PreTIS specifications


Unique identifier OMICS_14194
Name PreTIS
Alternative name Prediction of translation initiation sites
Interface Application programming interface
Restrictions to use None
Input data 5’ UTR of human mRNA sequence, homologous mouse mRNA sequences, translational start codons.
Output data Bar plot of predicted initiation confidence values for each start site, 5' UTR sequence with colored alternative start sites, table visualizing start site properties, result of the Blast search.
Programming languages Python
Computer skills Advanced
Stability Stable
Maintained Yes


  • Primates
    • Homo sapiens
  • Rodents
    • Mus musculus


  • person_outline Volkhard Helms <>

Publication for Prediction of translation initiation sites

PreTIS in publications

PMCID: 5448165
PMID: 28468958
DOI: 10.15252/msb.20177554

[…] with varying degree of complexity have been presented to estimate the contribution of processing, transcription and degradation rates from measured rna dynamics (zeisel et al, ; rabani et al, ; de pretis et al, ; cheng et al, ). two main conclusions arise from these studies. first, ordinary differential equations with only few parameters can accurately reflect mrna dynamics. secondly, changes […]

PMCID: 5543465
PMID: 28448071
DOI: 10.1038/ctg.2017.17

[…] , guarantor of the article: luca frulloni, md, phd., specific author contributions: conception or design of the work: luca frulloni and armando gabbrielli. acquisition of the data: nicolò de pretis, antonio amodio, laura bernardoni, pietro campagnola, fabiana capuano, stefano crinò, arianna massella. analysis or interpretation of data: nicolò de pretis, antonio amodio and luca frulloni. […]

PMCID: 5310924
PMID: 27443262
DOI: 10.1038/leu.2016.182

[…] gse76192 (, we thank dr j bradner, dr m esteban, dr giovanni tonon and dr j zuber for kindly sharing reagents. dr v bianchi, dr s de pretis, g melloni and p bora for discussion and suggestions on computational analyses. salvatore bianchi, thelma capra and luca rotta for technical support in ngs sequencing. dr b amati for critical […]

PMCID: 4963202
PMID: 27460974
DOI: 10.7554/eLife.15161.036

[…] expression profiles , , publicly available at ncbi gene expression omnibus (accession no: gse44672) , sabò a kress tr , pelizzola m , de pretis s , gorski mm , tesi a , morelli mj , bora p , doni m , verrecchia a , tonelli c , fagà g , bianchi v , ronchi a , low d , müller h , guccione e , campaner s , amati b , 2014 , selective […]

PMCID: 4611090
PMID: 26539129
DOI: 10.3389/fpsyg.2015.01494

[…] and underdown, ; rasic et al., ). studies have shown that about 23–32% of patients admitted to mental health care are caring for children (test et al., ; östman and hansson, ; fraser et al., ; pretis and dimova, ; maybery et al., ). given the number of families in germany and the overall rates of adult psychological illness, this suggests ~3.8 million children that have a parent […]

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PreTIS institution(s)
Center for Bioinformatics, Saarland University, Saarbrücken, Germany; Saarbrücken Graduate School of Computer Science, Saarland University, Saarbrücken, Germany

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