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Citations per year

Number of citations per year for the bioinformatics software tool prfreq
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This map represents all the scientific publications referring to prfreq per scientific context
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prfreq specifications

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Unique identifier OMICS_16371
Name prfreq
Software type Package/Module
Interface Command line interface
Restrictions to use None
Operating system Unix/Linux
Programming languages C
Computer skills Advanced
Stability Stable
Maintained Yes

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Publication for prfreq

prfreq citations

 (3)
library_books

Extensive Copy Number Variation of Young Genes across Stickleback Populations

2014
PLoS Genet
PMCID: 4256280
PMID: 25474574
DOI: 10.1371/journal.pgen.1004830

[…] utilized for processing genotypes and allele frequency spectra.To test for the influence of selection on the allele frequency spectrum of CNVs, we used a Poisson Random Field approach implemented in prfreq , which evaluates the expected allele frequency distributions given different demographic and selection models. We compared the estimates of the scaled selection coefficient γ of CNVs (both del […]

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Whole Exome Sequencing Reveals a Rapid Change in the Frequency of Rare Functional Variants in a Founding Population of Humans

2013
PLoS Genet
PMCID: 3784517
PMID: 24086152
DOI: 10.1371/journal.pgen.1003815

[…] oth the French and French-Canadian populations. First, we estimated the demographic parameters and the population selection parameter (γ = Ne(s)) using the Poisson Random Fields method implemented in prfreq . To estimate population demographic parameters, we used synonymous sites to test different demographic models and we find a significantly better fit for models that include a bottleneck and ex […]

library_books

The Role of Selection in Shaping Diversity of Natural M. tuberculosis Populations

2013
PLoS Pathog
PMCID: 3744410
PMID: 23966858
DOI: 10.1371/journal.ppat.1003543

[…] ectrum (SFS) from the global sample of M.tb is shown in the SFS is leptokurtic, with an irregular decay in the frequency of minor alleles as the counts increase. Results of analyses of the SFS using prfreq are shown in . The likelihood of the observed synonymous SFS was estimated for constant size, instantaneous expansion and exponential models of growth. The best fit growth model is of a sudden […]


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prfreq funding source(s)
This work was supported, in part, by grants from the National Institutes of Health and the National Science Foundation.

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