PrimeX | Structure refinement

Allows protein crystal structure refinement. PrimeX is an X-ray crystal structure refinement program which provides several features such as maximum-likelihood reciprocal-space minimization, simulated-annealing refinement, ligand placement, loop building and side-chain placement. The software uses the Optimized Potentials for Liquid Simulations-All Atom (OPLS-AA) force field with state-of-the-art computational technologies.