proABC statistics

To access cutting-edge analytics on consensus tools, life science contexts and associated fields, you will need to subscribe to our premium service.


Citations per year

Citations chart

Popular tool citations

chevron_left Structure-based B-cell epitope prediction chevron_right
Popular tools chart

Tool usage distribution map

Tool usage distribution map

Associated diseases

Associated diseases

proABC specifications


Unique identifier OMICS_06076
Name proABC
Alternative name prediction of Antibody Contacts
Interface Web user interface
Restrictions to use None
Computer skills Basic
Stability Stable
Maintained Yes

Publication for prediction of Antibody Contacts

proABC in publications

PMCID: 5889503
DOI: 10.22034/ibj.22.3.180

[…] considering the importance of antibody engineering, we aimed to extend our knowledge on functionally important residues of ligand-binding site in ofatumumab antibody variable region through proabc (prediction of antibody contacts) methodology[]. high affinity variants of antibody were selected according to the results of docking programs[] and molecular dynamics, which is a computer […]

PMCID: 5438104
PMID: 28542173
DOI: 10.1371/journal.pbio.2001390

[…] are unknown. insertions in 46 genes resulted in mutants with growth defects in defined liquid but not in solid rich media ( and ). among those, we identified mutations in genes involved in proline (proabc), biotin (bioafd), and purine and pyrimidine (carb, pyrbf, and purefhlmnqs) biosynthesis. these observations validated our experimental approach since the defined medium used in the screen […]

PMCID: 4528170
PMID: 26300863
DOI: 10.3389/fmicb.2015.00795

[…] orf00247, orf00248, and orf00252) participated in pyrimidine metabolism, and all of these genes were significantly up-regulated in alkaline stress. the carab (orf00250 and orf00251) operons and proabc (orf02358, orf023587, orf00819), which are involved in arginine and proline metabolism, also showed significant up-regulation under alkaline stress. koo et al. () also reported […]

PMCID: 4719070
PMID: 25971595
DOI: 10.1093/bib/bbv027

[…] over the past 2 years there has been an increasing interest in developing methodologies that predict specific paratope residues. there are currently three methods which address this problem: proabc [], antibody i-patch [] and ismblab-ppi []. proabc is a rf-based machine learning protocol, which requires only the sequence of the antibody on input. antibody i-patch is a statistical method, […]

PMCID: 4391529
PMID: 25879753
DOI: 10.1186/s12866-015-0404-x

[…] in the relative abundance of transcript corresponding to the repertory of genes presumably involved in k+ uptake (kup and kdpabcde), glutamate synthesis (glna, gltab and gdha) and proline syntheis (proabc) showed no significant up-regulation. instead, glna and gltd were down-regulated after both sucrose and salt stresses (figure b). accordingly, three protein spots whose intensities decreased […]

To access a full list of publications, you will need to upgrade to our premium service.

proABC institution(s)
Department of Physics, Sapienza University and Istituto Pasteur - Fondazione Cenci Bolognetti, Rome, Italy

proABC reviews

star_border star_border star_border star_border star_border
star star star star star

Be the first to review proABC