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Cristina Clement - Professor (Assistant) • Doctorate/PhD
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Cristina Clement

Professor (Assistant) • Doctorate/PhD

Cornell University • Weill Cornell Medicine • New York City, United States of America

I am currently Research Assistant Professor assigned to the Radiation/Oncology Department at the Weill Cornell medicine. I have a long and well-documented track record of accomplished and productive research projects in the field of mass…

Skills and expertise

Omics and technologies

  • MS-based untargeted proteomics

Software tools and databases

  • MaxQuant
  • PEAKS
  • Scaffold

Maths and IT

  • Bioinformatics
  • Data Mining

Life Science

  • Biochemistry
  • Cancer Research
  • Chemistry
  • Immunology
  • Molecular Biology
  • Pharmacology
  • Structural Biology
  • Systems Biology

Health Science

  • Drug Discovery
  • Personalized Medicine
  • Toxicology
  • Translational Research

General Skills

  • Analytics
  • Quality control
  • Scientific writing

Languages

  • English

Work experience

Resaerch Assistant Professor
Radiation Oncology-Weill Cornell Medicine - 1300 York Avenue
May 2019 - Today

Additional information

Contributions to Science (selected manuscripts)
1) In the laboratory of Dr. Laura Santambrogio at Albert Einstein College, I was the first to develop the proteomic and peptidomics assays coupled with advanced bioinformatics analysis of the molecular and cellular pathways for analysis of the human lymph and characterization its self-antigen peptide repertoire available for MHC II presentation. The global proteomics/peptidomics analysis was coupled with the development of cell-free systems, including isolated organelles such as late endosomes, plasma membrane, and cytosol, as well as enzymatic-based assays aimed to characterize the differential antigen-processing pathways that generate the peptidome of the human lymph.
2) In the lab of Dr. Laura Santambrogio I was the first to develop the redox proteomics and lipidomics assays coupled with high-throughput analysis of post-translational modifications capable of revealing the molecular mechanisms related to the effects of “oxidative stress” in aging, and other proinflammatory situations.
3) In the lab of Dr. Laura Santambrogio, I was the first to develop the peptidomics/proteomics assays aimed to discover the neopeptides epitopes, potential biomarkers of juvenile idiopathic arthritis (JIA). These assays, followed further by immunological functional validations, highlighted transthyretin as a biomarker of JIA disease.