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Philippe ROCHE - PI
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Philippe ROCHE

PI
French National Centre for Scientific Research • Paris • France

Skills and expertise

Fields of interest
  • Drug design
  • Synthetic biology
  • Protein interaction analysis
Languages
  • English
  • French
Programming languages
  • Perl
  • Python
  • Shell (Bash)

Bioinformatics projects

TOOLS MAINTAINED

2P2Idb

Dataset

2P2Idb

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A hand-curated structural database dedicated to protein-protein interactions with known orthosteric modulators. 2P2Idb includes all interactions for which both the protein-protein and protein-ligand…

Fields of interest

Drug design
Determines the interaction strength between two bound molecules of a given…
Constructs custom chemical genetics libraries for gene-sets of interest.…
Provides a native interface to the GROMACS molecular dynamics (MD) engine.…
Synthetic biology
Aims to assemble multiple DNA fragments in a single reaction using a…
Enables synthetic gene designers to evaluate their own constructs and put codon…
Identifies the most diverse randomer that is free of recognition sites for any…
Protein interaction analysis
Allows users to predict heme binding residues (HEMEs). For HEMEsPred, several…
Aggregates multiples types of data to determine transcription factors (TFs)…
Permits to study the dynamical features of gene regulatory circuits without the…