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Ren-Hua Chung
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Ren-Hua Chung

Division of Biostatistics and Bioinformatics, Institute of Population Health Sciences, National Health Research Institutes, Zhunan, Miaoli, Taiwan

Skills and expertise

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TOOLS MAINTAINED

PUPPI

Desktop

PUPPI / Pathway analysis Using Protein-Protein Interaction networks

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A pathway association test for genome-wide association studies (GWAS) with case-control samples. PUPPI aggregates the interaction signals in protein-protein interaction (PPI) networks within a…

GCORE-sib

Desktop

GCORE-sib

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An efficient gene-gene interaction test for discordant sib pairs (DSPs), which is suitable for genome-wide interaction analysis for single nucleotide polymorphisms (SNP) pairs in DSPs. We used…

GESDB

Dataset

GESDB / Genetic Epidemiology Simulation Database

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A platform for sharing simulation data and discussion of simulation techniques for human genetic studies. GESDB contains simulation scripts, simulated data, and documentations from published…

GCORE

Desktop

GCORE

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An efficient family-based gene-gene interaction test for trios (i.e., two parents and one affected sib). The GCORE compares interlocus correlations at two SNPs between the transmitted and…

OPTPDT

Desktop

OPTPDT / Optimal P-value Threshold Pedigree Disequilibrium Test

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A multi-SNP association test using a variable p-value threshold algorithm to select SNPs with the strongest association signal at a particular p-value threshold. The OPTPDT will be helpful for…

Pathway-PDT

Desktop

Pathway-PDT

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Uses the framework of pedigree disequilibrium test (PDT) for general family data, to perform pathway analysis based on raw genotypes in family-based GWAS. Pathway-PDT also can be more powerful than…

SeqSIMLA

Desktop

SeqSIMLA

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A simulation tool that can simulate sequence data with user-specified disease and quantitative trait models. SeqSIMLA can efficiently simulate sequence data with disease or quantitative trait models…

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