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Division of Biostatistics and Bioinformatics, Institute of Population Health Sciences, National Health Research Institutes, Zhunan, Miaoli, Taiwan

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Tools maintained by Ren-Hua Chung

PUPPI
Desktop

PUPPI Pathway analysis Using Protein-Protein Interaction networks

A pathway association test for genome-wide association studies (GWAS) with…

A pathway association test for genome-wide association studies (GWAS) with case-control samples. PUPPI aggregates the interaction signals in protein-protein interaction (PPI) networks within a…

GCORE-sib
Desktop

GCORE-sib

An efficient gene-gene interaction test for discordant sib pairs (DSPs), which…

An efficient gene-gene interaction test for discordant sib pairs (DSPs), which is suitable for genome-wide interaction analysis for single nucleotide polymorphisms (SNP) pairs in DSPs. We used…

GESDB
Dataset

GESDB Genetic Epidemiology Simulation Database

A platform for sharing simulation data and discussion of simulation techniques…

A platform for sharing simulation data and discussion of simulation techniques for human genetic studies. GESDB contains simulation scripts, simulated data, and documentations from published…

GCORE
Desktop

GCORE

An efficient family-based gene-gene interaction test for trios (i.e., two…

An efficient family-based gene-gene interaction test for trios (i.e., two parents and one affected sib). The GCORE compares interlocus correlations at two SNPs between the transmitted and…

OPTPDT
Desktop

OPTPDT Optimal P-value Threshold Pedigree Disequilibrium Test

A multi-SNP association test using a variable p-value threshold algorithm to…

A multi-SNP association test using a variable p-value threshold algorithm to select SNPs with the strongest association signal at a particular p-value threshold. The OPTPDT will be helpful for…

Pathway-PDT
Desktop

Pathway-PDT

Uses the framework of pedigree disequilibrium test (PDT) for general family…

Uses the framework of pedigree disequilibrium test (PDT) for general family data, to perform pathway analysis based on raw genotypes in family-based GWAS. Pathway-PDT also can be more powerful than…

SeqSIMLA
Desktop

SeqSIMLA

A simulation tool that can simulate sequence data with user-specified disease…

A simulation tool that can simulate sequence data with user-specified disease and quantitative trait models. SeqSIMLA can efficiently simulate sequence data with disease or quantitative trait models…

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