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张开明

learning
Shanghai Jiao Tong University • Shanghai • China

Skills and expertise

Fields of interest
  • Genome edition
  • RNA-seq analysis
  • DNA methylation array analysis
Languages
  • Chinese
Programming languages
  • Python

Fields of interest

Genome edition
Serves as a calculation and visualization tool for high-throughput CRISPR…
Creates single-guide RNA (sgRNA) for clustered regularly interspaced short…
Constructs optimal gRNAs for the CRISPR-Cpf1 system. CRISPR-DT can take into…
RNA-seq analysis
Consists of a supervised learning approach to integrate expression quantitative…
Serves for identifying regulons and validating gene regulatory networks.…
Enables adaptive correlation and covariance matrix shrinkage. CorShrink is a…
DNA methylation array analysis
Assists users to detect gene probes with different means or variances between…
Enables to build custom genome browsers. GIVe is a programming library allowing…
Extends the Integrative Genomics Viewer (IGV) with feature for curation…