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Summarizes and displays scored quantitative protein interaction data in intuitive ways. ProHits-viz consists of four data analysis and image generation tools complemented by interactive viewers. The analysis tools can (i) cluster baits and prey for dot plot images, (ii) perform correlation analysis, (iii) calculate prey specificity scores and, (iv) generate detailed bait–bait comparisons. This method enables visualization of the results from the dot plot and correlation tools directly in the browser.

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ProHits-viz classification

ProHits-viz specifications

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Web user interface
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ProHits-viz support



  • Anne-Claude Gingras <>


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Lunenfeld-Tanenbaum Research Institute, Sinai Health System, Toronto, ON, Canada; Saw Swee Hock School of Public Health, National University of Singapore and National University Health System, Singapore; Institute of Molecular and Cell Biology, Agency for Science, Technology, and Research, Singapore; Department of Molecular Genetics, University of Toronto, Toronto, ON, Canada; Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada; Department of Medical Biophysics, University of Toronto, Toronto, ON, Canada; Department of Pathology, University of Michigan, Ann Arbor, MI, USA; Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, MI, USA

Funding source(s)

Supported by the Government of Canada through Genome Canada and the Ontario Genomics Institute (grant nos. OGI-088 and OGI-097), the Canadian Institutes of Health Research (Foundation grant no. FDN143301), the US National Institutes of Health (grant no. 5R01GM94231) and the Singapore Ministry of Education (grant no. MOE T2-2-084).

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