Analyzes data from thousands of prokaryotic genomes in order to understand what drives the evolution and diversity of this superfamily. The Prokaryotic AARS Database is an online resource that was develop for the rapid and sensitive detection of AARS proteins encoded in genome sequences. It helps to identify organisms with alternative pathways that are involved in maintaining the fidelity of the genetic code.
Bioinformatics Laboratory, Department of Biochemistry and Biotechnology, University of Thessaly, Larissa, Greece; Molecular Microbiology Laboratory, Department of Biochemistry and Biotechnology, University of Thessaly, Larissa, Greece; Department of Microbiology, The Ohio State University, Columbus, OH, USA; Genétique Moléculaire, Génomique, Microbiologie, CNRS, Université de Strasbourg, Strasbourg, France; Department of Biochemistry, School of Medicine, University of Patras, Patras, Greece
Prokaryotic AARS Database funding source(s)
This work was supported by ‘Fondation Sante’ Grants 2016 (E515), ‘ARISTEIA’ and ‘ARISTEIA II’ Action of the ‘OPERATIONAL PROGRAMME EDUCATION AND LIFELONG LEARNING’, the European Social Fund (ESF) and National Resources [MIS 1225, No. D608, 4288]; Postgraduate Program ‘Applications of Molecular Biology-Genetics, Diagnostic Biomarkers’ [code 3817] of the University of Thessaly, School of Health Sciences, Department of Biochemistry & Biotechnology; French National Program ‘Investissement d’Avenir’ administered by the ‘Agence National de la Recherche’ (ANR), ‘MitoCross’ Laboratory of Excellence (Labex) [ANR-10-IDEX-0002-02] and the University of Strasbourg; National Science Foundation [MCB 1412611].