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Prodigal | Prokaryotic gene recognition and translation initiation site identification

A gene-finding program for microbial genomes. The goals of Prodigal were to attain greater sensitivity in identifying existing genes, to predict translation initiation sites more accurately, and to minimize the number of false positive predictions. The results of Prodigal were compared to existing methods for both purely experimentally verified genes as well as curated Genbank files for a number of genomes. Prodigal's performance was found to be comparable or better to existing methods in the prediction of genes while also predicting fewer overall genes.

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Prodigal classification

Prodigal specifications

Unique identifier:
Software type:
Restrictions to use:
Programming languages:
Computer skills:
PROkaryotic DYnamic programming Gene-finding ALgorithm
Command line interface
Operating system:
Unix/Linux, Mac OS, Windows
GNU General Public License version 2.0

Prodigal distribution


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Computational Biology and Bioinformatics Group, Oak Ridge National Laboratory, Oak Ridge, TN, USA

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