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prokaryotic Virus Orthologous Groups pVOGs


Represents a comprehensive set of orthologous gene families shared across multiple complete genomes of viruses that infect bacterial or archaeal hosts. The uses of pVOGs include functional annotation of viral proteins, identification of genes and viruses in uncharacterized DNA samples, phylogenetic analysis and large-scale comparative genomics projects. This database provides evolutionary gene families from nearly 3000 complete genomes of viruses that infect bacteria or archaea as a pre-computed resource.

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pVOGs classification

  • Viruses

pVOGs specifications

Restrictions to use:
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pVOGs support



  • David Kristensen <>


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Department of Biomedical Engineering, College of Engineering, University of Iowa, Iowa City, IA, USA; National Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, Bethesda, MD, USA

Funding source(s)

This work was supported by the Department of Biomedical Engineering at the University of Iowa and the Intramural Research Program of the National Library of Medicine at the National Institutes of Health.

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