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pRolocdata specifications


Unique identifier OMICS_18349
Name pRolocdata
Software type Package/Module
Interface Command line interface
Restrictions to use None
Operating system Unix/Linux
Programming languages R
License GNU General Public License version 2.0
Computer skills Advanced
Version 1.19.5
Stability Stable
Biobase, utils, testthat, R(>=2.15), MSnbase, pRoloc(>=1.13.8)
Maintained Yes


  • hyperLOPIT




No version available



  • person_outline Laurent Gatto
  • person_outline Kathryn Lilley

Publications for pRolocdata

pRolocdata citations


Time, space, and disorder in the expanding proteome universe

PMCID: 5573936
PMID: 28145059
DOI: 10.1002/pmic.201600399

[…] ion, coverage of sub‐cellular niches and reduction of false assignments to different sub‐cellular niches; differential centrifugation and in‐solution digests have been used as technical variations of hyperLOPIT . LOPIT studies have revealed that many more proteins than expected are present in multiple locations of the cell. This observation gives rise to intriguing questions including how multiple […]


A draft map of the mouse pluripotent stem cell spatial proteome

Nat Commun
PMCID: 4729960
PMID: 26754106
DOI: 10.1038/ncomms9992

[…] The hyperLOPIT technique is a systematic and accurate assay for characterizing the localization of thousands of proteins in a single experiment, and is applicable to many biological model systems. Applica […]

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pRolocdata institution(s)
Cambridge Centre for Proteomics, Department of Biochemistry, University of Cambridge, Cambridge, UK; Computational Proteomics Unit, Department of Biochemistry, University of Cambridge, Cambridge, UK; Université Grenoble Alpes, CEA, INSERM, CNRS, Grenoble, France
pRolocdata funding source(s)
Supported by the European Union 7th Framework Program (PRIME-XS Project, Grant No. 262067), the BBSRC Tools and Resources Development Fund (Award No. BB/K00137X/1), the Proteomics French Infrastructure (ProFI, ANR-10-INBS-08), the BBSRC Grant No. BB/D526088/1, the BBSRC Grant No. BB/E024777/ and a generous gift from King Abdullah University for Science and Technology, Saudi Arabia, and the BBSRC CASE studentship (BB/I016147/1).

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