PrologP statistics

Tool stats & trends

Looking to identify usage trends or leading experts?

PrologP specifications

Information


Unique identifier OMICS_16259
Name PrologP
Software type Package/Module
Interface Graphical user interface
Restrictions to use License purchase required
Operating system Windows
Computer skills Medium
Stability Stable
Maintained Yes

Versioning


No version available

Maintainer


  • person_outline PrologP Team

Additional information


A registration is needed to access to tools.

PrologP citations

 (3)
library_books

Design, synthesis, crystallization and biological evaluation of new symmetrical biscationic compounds as selective inhibitors of human Choline Kinase α1 (ChoKα1)

2016
Sci Rep
PMCID: 4814829
PMID: 27029499
DOI: 10.1038/srep23793

[…] 0 μM), indicating high affinity for the enzyme. These results agree with the first experimental validation of the docking studies described above. summarizes the clog P calculated by Pallas (3.8.1.1. PrologP) and the inhibitory effect on purified human ChoKα1 activity.Of all tested compounds, the ones that present an alkylamine or a cycloalkylamine substituted at position 4 of the pyridinium or qu […]

library_books

Flash Nanoprecipitation: Prediction and Enhancement of Particle Stability via Drug Structure

2014
Mol Pharm
PMCID: 3993913
PMID: 24484077
DOI: 10.1021/mp500025e

[…] GlaxoSmithKline and Pfizer) and the ACD company also developed LogD model. There are various similar algorithm models available (e.g., ALogP, ALogPs, ABLogP, AClogP, COSMOFraq, cLogP, MlogP, MiLogP, ProLogP, XLogP, and LogKOW). Each algorithm model has its own strengths and exceptions,, but the comparable LogD model is not developed for all LogP models. Depending on the water miscible organic sol […]

library_books

In Silico Studies in Probing the Role of Kinetic and Structural Effects of Different Drugs for the Reactivation of Tabun Inhibited AChE

2013
PLoS One
PMCID: 3846473
PMID: 24312449
DOI: 10.1371/journal.pone.0079591

[…] lays an important role in rational drug design as it is of primary significance in drug absorption and distribution. The octanol/water partition coefficient (LogP) calculation was performed using the PrologP module of the Pallas 3413 software . Oximes are in general polar compounds, particularly when they are charged, and hence they are highly soluble in water. A negative value of LogP reflects th […]

Citations

Looking to check out a full list of citations?

PrologP institution(s)
CompuDrug International, Bal Harbor, Florida, FL, USA

PrologP reviews

star_border star_border star_border star_border star_border
star star star star star

Be the first to review PrologP