Tool stats & trends
Looking to identify usage trends or leading experts?
|Interface||Graphical user interface|
|Restrictions to use||License purchase required|
No version available
- person_outline PrologP Team
Design, synthesis, crystallization and biological evaluation of new symmetrical biscationic compounds as selective inhibitors of human Choline Kinase α1 (ChoKα1)
[…] 0 μM), indicating high affinity for the enzyme. These results agree with the first experimental validation of the docking studies described above. summarizes the clog P calculated by Pallas (18.104.22.168. PrologP) and the inhibitory effect on purified human ChoKα1 activity.Of all tested compounds, the ones that present an alkylamine or a cycloalkylamine substituted at position 4 of the pyridinium or qu […]
Flash Nanoprecipitation: Prediction and Enhancement of Particle Stability via Drug Structure
[…] GlaxoSmithKline and Pfizer) and the ACD company also developed LogD model. There are various similar algorithm models available (e.g., ALogP, ALogPs, ABLogP, AClogP, COSMOFraq, cLogP, MlogP, MiLogP, ProLogP, XLogP, and LogKOW). Each algorithm model has its own strengths and exceptions,, but the comparable LogD model is not developed for all LogP models. Depending on the water miscible organic sol […]
In Silico Studies in Probing the Role of Kinetic and Structural Effects of Different Drugs for the Reactivation of Tabun Inhibited AChE
[…] lays an important role in rational drug design as it is of primary significance in drug absorption and distribution. The octanol/water partition coefficient (LogP) calculation was performed using the PrologP module of the Pallas 3413 software . Oximes are in general polar compounds, particularly when they are charged, and hence they are highly soluble in water. A negative value of LogP reflects th […]
Looking to check out a full list of citations?
Be the first to review PrologP