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Proteasomal cleavage detection software tools | Immunoinformatics

Proteasomes, major proteolytic sites in eukaryotic cells, play an important part in major histocompatibility class I (MHC I) ligand generation and thus in the regulation of specific immune responses. Their cleavage specificity is of outstanding…
ProteaMAlg
Desktop

ProteaMAlg Proteasome Modeling Algorithm

Allows the description of kinetics of specific protein fragments generated by…

Allows the description of kinetics of specific protein fragments generated by 20S proteasomes in different conditions. ProteaMAlg is a model that aims to improve the analysis and predictions of the…

PCPS
Web

PCPS Proteasome Cleavage Prediction Server

Predicts cleavage sites of the constitutive proteasome and the…

Predicts cleavage sites of the constitutive proteasome and the immunoproteasome. PCPS is a web server that allows the prediction of proteasome and immunoproteasome cleavage through N-gram models. The…

Pcleavage
Desktop
Web

Pcleavage

A support vector machine based method for the prediction of constitutive as…

A support vector machine based method for the prediction of constitutive as well as immunoproteasome cleavage sites in antigenic sequences. Pcleavage achieved Matthew's correlation coefficents…

PAProC
Web

PAProC Prediction Algorithm for Proteasomal Cleavages

A prediction tool for cleavages by human and yeast proteasomes, based on…

A prediction tool for cleavages by human and yeast proteasomes, based on experimental cleavage data. PAProC is particularly useful for immunologists working on antigen processing and the prediction…

NetChop
Web

NetChop

Produces neural network predictions for cleavage sites of the human proteasome.…

Produces neural network predictions for cleavage sites of the human proteasome. NetChop has been trained on human data only, and will therefore presumably have better performance for prediction of…

MAPPP
Web

MAPPP MHC-I Antigenic Peptide Processing Prediction

A bioinformatics tool for the prediction of potential antigenic epitopes…

A bioinformatics tool for the prediction of potential antigenic epitopes presented on the cell surface by major histocompatibility complex class I (MHC I) molecules to CD8 positive T lymphocytes.…

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