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ProteDNA | A sequence-based predictor of sequence-specific DNA-binding residues in transcription factors

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A sequence-based predictor for identifying the sequence-specific binding residues in a transcription factor (TF). Concerning protein-DNA interactions, there are two types of binding mechanisms involved, namely sequence-specific binding and nonspecific binding. Sequence-specific bindings occur between protein sidechains and nucleotide bases and correspond to sequence-specific recognition of genes. Therefore, sequence-specific bindings are essential for correct gene regulation. In this respect, ProteDNA is distinctive since it has been designed to identify sequence-specific binding residues. In order to accommodate users with different application needs, ProteDNA has been designed to operate under two modes, namely, the high-precision mode and the balanced mode.

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ProteDNA classification

ProteDNA specifications

Unique identifier:
OMICS_08390
Restrictions to use:
None
Input format:
FASTA
Stability:
Stable
Interface:
Web user interface
Input data:
Protein sequence(s)
Computer skills:
Basic
Maintained:
Yes

ProteDNA support

Maintainer

  • Yen-Jen Oyang <>

Credits

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Publications

Institution(s)

Department of Computer Science and Information Engineering, National Taiwan University, Taipei, Taiwan, China

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