A comprehensive sequence database of voltage-gated potassium channels (VKCs) from Eukaryotes, Bacteria and Archaea, designed to serve as a resource for research on VKC evolution and structure/function relationships. Protein sequences, corresponding nucleic acid sequences of open reading frames, references, information on the organisms of origin of each channel and functional data are stored in this database.
A database for pain stimulating and pain relieving compounds, which bind or potentially bind to ion channels, such as TRPV1, TRPM8, TRPA1, hERG, TREK1, P2X, ASIC or voltage-gated sodium channels. The database consists of about 8,700 ligands, which are characterized by experimentally measured binding affinities. Additionally, 100,000 putative ligands are included.
This is a database of comparative protein structure models of MIP (Major Intrinsic Protein) family of proteins. The nearly completed sets of MIPs have been identified from the completed genome sequence of organisms available at NCBI. The structural models of MIP proteins were created by defined protocol. The database aims to provide key information of MIPs in particular based on sequence as well as structures. This will further help to decipher the function of uncharacterized MIPs.
A resource designed for scientists, who look for a convenient way to access data about individual plant membrane proteins and membrane protein families. Currently, ARAMEMNON provides membrane protein data of nine plant species.
An information management framework for comprehensive ion channel information. Channelpedia is a knowledge base system centered on genetically expressed ion channel models and it encourages researchers of the field to contribute, build and refine the information through an interactive wiki-like interface. It is web-based, freely accessible and currently contains 187 annotated ion channels with 50 Hodgkin-Huxley models.
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