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Circular permutation detection software tools | Protein structure data analysis

Circular permutation (CP) is a protein structural rearrangement phenomenon, through which nature allows structural homologs to have different locations of termini and thus varied activities, stabilities and functional properties. It can be applied…
CE-CP
Web

CE-CP Combinatorial Extension for Circular Permutations

Allows the structural comparison of circularly permuted proteins. CE-CP was…

Allows the structural comparison of circularly permuted proteins. CE-CP was designed to be user friendly and is integrated into the RCSB Protein Data Bank. It was tested on two collections of…

CPred
Web

CPred

Predicts viable circular permutation (CP) sites by integrating four machine…

Predicts viable circular permutation (CP) sites by integrating four machine learning methods, inclusive of artificial neural network (ANN), support vector machine (SVM), random forest and…

SISYPHUS
Dataset

SISYPHUS

Contains a collection of manually curated structural alignments and their…

Contains a collection of manually curated structural alignments and their inter-relationships. The multiple alignments are constructed for protein structural regions that range from oligomeric…

CPDB
Dataset

CPDB Circular Permutation DataBase

A hierarchical categorization in which pairs of circular permutants are grouped…

A hierarchical categorization in which pairs of circular permutants are grouped into CP clusters, which are further grouped into folds and in turn classes. Additions to CPDB include a useful set of…

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