Simplifies search for a given sequence of domains in various genomes, identification of domain fusion events, recognition of gene products with identical or similar domain compositions. PRODOC determines proteins with a circularly permuted or jumbled arrangement of the order of domains. It allows comparison of domain organization between two genomes of interest. This tool assists users to suggest possibilities for the functional annotation of domain-unassigned regions.
Molecular Biophysics Unit, Indian Institute of Science, Bangalore, India; Super Computer Education and Research Center, Indian Institute of Science, Bangalore, India
PRODOC funding source(s)
Supported by the award of a Senior Fellowship in Biomedical Sciences by the Wellcome Trust, UK, as well as by the computational genomics project supported by the Department of Biotechnology, Government of India and by fellowships from the Council of Scientific and Industrial Research, Government of India.