Predicts the possible impact of an amino acid substitution on the structure and function of a human protein. PolyPhen predicts the functional significance of an allele replacement from its individual features by a Naïve Bayes classifier. The web application allows users to (i) predict the effect of a single-residue substitution or reference single nucleotide polymorphism SNP, (ii) analyze SNPs in a batch mode, and (iii) search in a database of precomputed predictions for the whole human exome sequence space.
1 - 5 of 142
results
filter_list
Filters / Sort by
1 - 5 of 142
results
Provides functional analysis of protein sequences. InterPro is a software which allows to classify sequences into protein families and to predict the presence of important domains and sites. The software combines predictive models, known as signatures, from a range of different protein family databases that have different biological focuses and use different methodological approaches to classify protein families and domains.
Gives access to many free software tools for sequence analysis. EMBOSS aims to serve the molecular biology community. It permits the creation and the release of software in an open source spirit. This tool is useful for sequence analysis into a seamless whole. It is free of charge and is available in open source.
Allows automated protein structure prediction and structure-based function annotation. I-TASSER constructs, starting from the amino acid sequence, 3D structural models by reassembling fragments excised from threading templates. I-TASSER servers provides a confidence score (C-score) to estimate the models’ global accuracy. The I-TASSER Suite pipeline was tested in community-wide structure and function prediction experiments, including CASP10 and CAMEO.
Provides a suite of methods important for the prediction of protein structural and functional features. predictProtein is a web server that incorporates over 30 tools. This software searches up-to-date public sequence databases, creates alignments, and predicts aspects of protein structure and function. It can help when little is known about the protein in question. For medium-to-high throughput analyses, downloadable software packages and the PredictProtein Machine Image (PPMI) are available.
1 - 5 of 15
results
filter_list
Filters / Sort by
1 - 5 of 303
results
filter_list
Filters / Sort by
1 - 5 of 303
results

Discover our proposed protocols.
They are easy to use or edit to meet your needs.
They are easy to use or edit to meet your needs.
Genome and transcriptome sequencing identifies breeding targets in the orphan crop tef (Eragrostis tef)
Tools (4):
InterPro, PRIAM, BLASTX, TBLASTN
Topics (1):
Protein sequence analysis
Transcriptomic analysis of the phytopathogenic oomycete Phytophthora cactorum provides insights into infection related effectors
Tools (3):
InterPro, Blast2GO, BLASTN
Topics (2):
Protein sequence analysis, Phytophthora infestans
Genome structure of cotton revealed by a genome wide SSR genetic map constructed from a BC1 population between gossypium hirsutum and G. barbadense
Tools (3):
Blast2GO, BLASTX, InterPro
Topics (1):
Protein sequence analysis
Hsp12.6 Expression Is Inducible by Host Immunity in Adult Worms of the Parasitic Nematode Nippostrongylus brasiliensis
Tools (4):
InterProScan, FingerPRINTScan, Clustal W, PMDB
Topics (1):
Protein sequence analysis
Effects of elevated seawater pCO2 on gene expression patterns in the gills of the green crab, Carcinus maenas
Tools (3):
BLASTX, Blast2GO, InterPro
Topics (1):
Protein sequence analysis