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Protein-metal binding databases | Interaction data analysis

It has been estimated that 30–40% of proteins require one or more metal ions to be able to carry out their biological function in cells (Andreini et al., 2009Andreini et al., 2008). This proportion depends on the specific organism or tissue under consideration, which affects also the relative usage of the various metals. Additionally, metal ions play a decisive role in stabilizing the structure of nucleic acids (Pechlaner and Sigel, 2012).

Source text:
(Andreini et al., 2013) MetalPDB: a database of metal sites in biological macromolecular structures. Nucleic Acids Res.

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