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Methylation site prediction software tools | Post-translational modification analysis

Protein methylation is one type of reversible post-translational modifications (PTMs), which plays vital roles in many cellular processes such as transcription activity, DNA repair. Experimental identification of methylation sites on proteins…
GPS-MSP
Web
Desktop

GPS-MSP GPS-Methyl-group Specific Predictor

Provides a useful method for the computational analysis of protein methylation.…

Provides a useful method for the computational analysis of protein methylation. GPS-MSP is a computational tool for the prediction of general protein methylation sites and methylation types of…

MePred-RF
Web

MePred-RF

Predicts and analyzes protein methylation sites, particularly for large-scale…

Predicts and analyzes protein methylation sites, particularly for large-scale genome projects. MePred-RF is a machine-learning-based method for protein methylation site prediction. This approach…

PSSMe
Web

PSSMe Prediction of Species-Specific Methylation sites

A tool based on information gain (IG) feature optimization method for…

A tool based on information gain (IG) feature optimization method for species-specific methylation site prediction. The IG method was adopted to analyze the importance and contribution of each…

iPTM-mLys
Web

iPTM-mLys

Identifies multiple lysine post-translational modification (PTM) sites and…

Identifies multiple lysine post-translational modification (PTM) sites and their different types. iPTM-mLys represents the first multi-label PTM predictor ever established. The novel predictor is…

PMes
Web

PMes

Identifies methylation sites based on an enhanced feature encoding scheme for…

Identifies methylation sites based on an enhanced feature encoding scheme for extracting the most informative amino acids features. PMes is an enhanced feature encoding scheme that incorporates the…

PRmePRed
Web

PRmePRed Protein aRginine methylation PRediction

Predicts arginine methylation sites in proteins. PRmePRed is a predictor based…

Predicts arginine methylation sites in proteins. PRmePRed is a predictor based on sequence and structure derived features, using support vector machines (SVMs).

PLMLA
Web

PLMLA

Predicts lysine methylation and lysine acetylation only from the protein…

Predicts lysine methylation and lysine acetylation only from the protein primary sequence. PLMLA is an algorithm implemented in a web app that consider not only protein sequence information but also…

iLM-2L
Desktop

iLM-2L

Predicts lysine methylation sites and their methylation degrees. iLM-2L is…

Predicts lysine methylation sites and their methylation degrees. iLM-2L is based on composition of k-spaced amino acid pairs feature coding scheme and support vector machine (SVM) algorithm. It…

PTMProber
Web

PTMProber

A homology-based pipeline that allows identification of potential modification…

A homology-based pipeline that allows identification of potential modification sites for most of the proteomes lacking post-translational modifications (PTMs) data. PTMProber provides a unique…

PyTMs
Desktop

PyTMs

A plugin implemented with the commonly used visualization software PyMOL. PyTMs…

A plugin implemented with the commonly used visualization software PyMOL. PyTMs enables users to introduce a set of common post-translational modifications (PTMs) into protein/peptide models and can…

iMethyl-PseAAC
Web

iMethyl-PseAAC

Predicts methylation sites in proteins. With the assistance of SVM, the…

Predicts methylation sites in proteins. With the assistance of SVM, the highlight of iMethyl-PseAAC is to employ amino acid sequence features extracted from the sequence evolution information via…

MASA
Web

MASA Methylation site based on the Accessible Surface Area

A web tool for identifying the protein methylation site based on the accessible…

A web tool for identifying the protein methylation site based on the accessible surface area (ASA) which is surrounding the modification site. MASA combines the support vector machine with the…

BPB-PPMS
Web

BPB-PPMS

An in silico online tool for identification of potential methylation sites from…

An in silico online tool for identification of potential methylation sites from protein sequences. The computational methodology is based on Bi-profile Bayes combined with support vector machines…

MethK
Web

MethK

Identifies lysine-methylated sites on histones and non-histone proteins. MethK…

Identifies lysine-methylated sites on histones and non-histone proteins. MethK is a web server that provides a user-friendly interface and predictive results. Users can submit a protein sequence and…

MeMo
Web

MeMo Protein Methylation Modification Prediction

An online tool for protein methylation site prediction employing the algorithm…

An online tool for protein methylation site prediction employing the algorithm of support vector machines (SVMs). Due to the data limitation our system focuses on methylated arginine and lysine…

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