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Solubility detection software tools | Protein structure data analysis

Recombinant protein technology is essential for conducting protein science and using proteins as materials in pharmaceutical or industrial applications. Although obtaining soluble proteins is still a major experimental obstacle, knowledge about…
ANTHEPROT
Desktop

ANTHEPROT

Allows protein sequence analysis. ANTHEPROT is able to interactively couple…

Allows protein sequence analysis. ANTHEPROT is able to interactively couple multiple alignments with secondary structure predictions. It can submit tasks on a remote server and retrieve data from a…

PaRSnIP
Desktop

PaRSnIP PRotein SolubIlity Predictor

Predicts protein solubility. PaRSnIP is based on the white-box nonlinear…

Predicts protein solubility. PaRSnIP is based on the white-box nonlinear predictive modeling technique gradient boosting machine (GBM). It employs two types of input features to distinguish between…

Protein-Sol
Web

Protein-Sol

Predicts protein solubility. Protein-sol returns the predicted solubility and…

Predicts protein solubility. Protein-sol returns the predicted solubility and other properties of an amino acid sequence in a graphical format. It was demonstrated with E. coli thioredoxin, known to…

SODA
Web

SODA protein SOlubility based on Disorder and Aggregation

Predicts the effects of sequence variations on protein solubility. SODA is a…

Predicts the effects of sequence variations on protein solubility. SODA is a method to exploit the concepts described above (aggregation and dis order propensity, hydrophobic profile, predicted…

Periscope
Web

Periscope PERIplasmic expreSsion Classifier for sOluble Protein Expression

A predictor for soluble protein expression in the periplasm of Escherichia…

A predictor for soluble protein expression in the periplasm of Escherichia coli. Periscope is a sequence-based predictor with a two-stage architecture that estimates the expression level and yield of…

ccSOL omics
Web

ccSOL omics

A method to perform large-scale solubility predictions of endogenous and…

A method to perform large-scale solubility predictions of endogenous and heterologous protein expression in E. coli.

PROSO II
Web

PROSO II PROtein SOlubility evaluator II

A web app using new classification methods and improvements in experimental…

A web app using new classification methods and improvements in experimental data to improve coverage and accuracy of proteins solubility predictions. They are based on a classifier exploiting subtle…

ccSol
Web

ccSol

A tool to predict the solubility of proteins based on their physicochemical…

A tool to predict the solubility of proteins based on their physicochemical properties.

ESPRESSO
Web
AquaSol
Web
Desktop

AquaSol

A web server for aqueous solubility prediction available through the ChemDB…

A web server for aqueous solubility prediction available through the ChemDB chemoinformatics portal. Aquasol predicts aqueous solubility of small molecules using undirected graph recursive neural…

eSOL
Dataset

eSOL

Provides information about the solubility of entire ensemble E.coli proteins…

Provides information about the solubility of entire ensemble E.coli proteins individually synthetized by PURE system that is chaperone free.

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