Assists in working on diseases such as HIV, cancer, complement diseases, and other autoimmune disorders. Protein WISDOM is an online tool that consists of two stages: (1) first it produces a rank-ordered list of amino acid sequences that will fold into a given template structure; and (2) then it validates these sequences by calculating either fold specificity or approximate binding affinity, or both.
Department of Chemical and Biological Engineering, Princeton University, Princeton, NJ, USA
Protein WISDOM funding source(s)
Supported by the NSF, NIH (R01 GM52032; R24 GM069 736), the US Environmental Protection Agency, EPA (R 832721-010); the NIH (P50GM071508-06); the National Defense Science and Engineering Graduate (NDSEG) Fellowship, 32 CFR 168a; and the National Science Foundation Graduate Research Fellowship under grant number DGE-1148900.