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Protocols
Proteome Discoverer specifications
Information
| Unique identifier | OMICS_04551 |
|---|---|
| Name | Proteome Discoverer |
| Alternative name | PD |
| Software type | Package/Module |
| Interface | Graphical user interface |
| Restrictions to use | License purchase required |
| Operating system | Windows |
| License | Commercial |
| Computer skills | Medium |
| Version | 2.1 |
| Stability | Stable |
| Requirements |
Mascot, Proteome Discover
|
| Maintained | No |
Subtools
- Feature Mapper
- LFQProfiler
- Minora Feature Detector
- Precuror Ions Quantifier
- Precursor Ions Area Detector
- Reporter Ions Quantifier
- RNP(xl)
Versioning
No version available
Documentation
Maintainer
Publication for Proteome Discoverer
Proteome Discoverer citations
(1766)Rapid labelling and covalent inhibition of intracellular native proteins using ligand directed N acyl N alkyl sulfonamide
[…] intensity precursor ions. Multiple charged peptides were chosen for MS/MS experiments due to their good fragmentation characteristics. MS/MS spectra were interpreted, and peak lists were generated by Proteome Discoverer 1.4.1.14 (Thermo Fisher Scientific). Searches were performed using the SEQUEST HT (Thermo Fisher Scientific) against the latest uniprot database for whole Human proteome (Homo sapi […]
Additional oxidative stress reroutes the global response of Aspergillus fumigatus to iron depletion
[…] Thermo raw files were processed by Proteome Discoverer 1.4 (Thermo). MS/MS spectra were searched against the AspGD protein database of A. fumigatus Af293 (www.aspergillusgenome.org/download/sequence/A_fumigatus_Af293/current/A_fumigatu […]
Identification of a unique Radical SAM methyltransferase required for the sp3 C methylation of an arginine residue of methyl coenzyme M reductase
[…] in the MS1 scan were calculated using the Minora Feature Detector node. Further quantification was performed using the consensus workflow performing retention time alignment and feature mapping. The Feature Mapper node groups detected features from the processing workflow allowing quantification across all raw files thereby performing gap filling. In ‘Peptide and Protein Filter’ node the minimum […]
Mutational disruption of the ABCC2 gene in fall armyworm, Spodoptera frugiperda, confers resistance to the Cry1Fa and Cry1A.105 insecticidal proteins
[…] t as 1 × 105. For each sample, the injection volume was adjusted per the protein assay to load 1 µg on column. Three technical replicates were applied with each sample.Proteins were identified by the Proteome Discoverer (version 1.4; Thermo Fisher Scientific, Waltham, MA, USA). The S. frugiperda protein database (1,786 sequences) from uniport was combined with a S. frugiperda ABCC2 (SfABCC2) prote […]
Proteome wide analysis of Anopheles culicifacies mosquito midgut: new insights into the mechanism of refractoriness
[…] LC/MS/MS derived data were searched and analyzed using Proteome Discoverer 1.4 (Thermo Scientific). The acquired MS/MS data were searched against UniProt mosquito database, a well curated database using SEQUEST algorithm. Search parameters used: trypsin e […]
Cigarette smoke and chewing tobacco alter expression of different sets of miRNAs in oral keratinocytes
[…] Proteome Discoverer (version 2.1.0.81) software suite (Thermo Fisher Scientific) was used for MS/MS searches using SEQUEST and Mascot (version 2.4.1; Matrix 617 Science) algorithms againt NCBI RefSeq […]
Citations
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