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ProtOn specifications


Unique identifier OMICS_24647
Name ProtOn
Alternative name Proteins Online
Software type Application/Script
Interface Web user interface
Restrictions to use None
Input format PDB
Computer skills Basic
Stability Stable
Maintained Yes


  • person_outline Evgeniy Aksianov

ProtOn citations


Comparative Genomics Reveals Thousands of Novel Chemosensory Genes and Massive Changes in Chemoreceptor Repertories across Chelicerates

Genome Biol Evol
PMCID: 5952958
DOI: 10.1093/gbe/evy081

[…] pies. Additionally, and very surprisingly, we detected 19 novel (out a total of 21) Obp-like genes in the centipede S. maritima. Our phylogenetic analysis of canonical OBP (from insects) and OBP-like proteins (, , online) does not support the reciprocal monophyly of these two gene families. Although some OBP-like sequences (such as MoccOPBl2, IscaOBPl2 and PtepOBPl3) are phylogenetically close to […]


The Genome Sequence of “Candidatus Fokinia solitaria”: Insights on Reductive Evolution in Rickettsiales

Genome Biol Evol
PMCID: 5905368
PMID: 29659807
DOI: 10.1093/gbe/evy072

[…] litator superfamily), and could complement metabolic deficiencies enabling direct uptake of small molecules from the host. The presence of multiple secretion systems (, online) and putative secreted proteins (, online), including an ankyrin repeat protein, likely enables F. solitaria to establish and regulate interactions with the host (). Surprisingly, many of these annotated proteins are typic […]


Homologous Recombination between Genetically Divergent Campylobacter fetus Lineages Supports Host Associated Speciation

Genome Biol Evol
PMCID: 5830970
PMID: 29608720
DOI: 10.1093/gbe/evy048

[…] r Cff/Cfv or Cft, a disproportionally high number encoded proteins related to DNA uptake and defense, such as competence, transformation system, restriction-modification system, and CRISPR/Cas system proteins (, online).Notably, 60 genes were exclusively shared between C. fetus ST69 and Cft strain 13S00388-15, which was isolated from Chelonoidis denticulata, a chelonian species closely related to […]


Parallel Evolution of Sperm Hyper Activation Ca2+ Channels

Genome Biol Evol
PMCID: 5553355
PMID: 28810709
DOI: 10.1093/gbe/evx131

[…] sked if any branch in the primate phylogeny had a dN/dS >1. We first analyzed the four core proteins CATSPER1-4 that form the Ca2+ pore. We detected elevated rates of dN/dS in each of these four core proteins (, , online). In addition to the core proteins, all five auxiliary transmembrane proteins CATSPERβ, CATSPERΔ, CATSPERγ, CATSPERε and CATSPERζ also show elevated rates of dN/dS. We found that […]


Structured Populations of Sulfolobus acidocaldarius with Susceptibility to Mobile Genetic Elements

Genome Biol Evol
PMCID: 5554439
PMID: 28633403
DOI: 10.1093/gbe/evx104

[…] genomes experienced a recent bottleneck or colonization event.To search for signals of selection among clades, we assessed whether the SNPs in the core genome changed the coding sequence of specific proteins (, online). Among core genes overall, there were ∼3.6×105 potential synonymous sites and 1.3×106 potential nonsynonymous sites. We observed 53 nonsynonymous SNPs and 41 synonymous SNPs in th […]


Gene Duplication Leads to Altered Membrane Topology of a Cytochrome P450 Enzyme in Seed Plants

Mol Biol Evol
PMCID: 5850782
PMID: 28505373
DOI: 10.1093/molbev/msx160

[…] ure of class II CYP73s. A four to five amino-acid insertion, located 13 residues upstream of the conserved heme-binding cysteine, and including positively charged residues, is present in all class II proteins (, online). Homology modeling locates this insertion in a loop on the heme proximal surface of the protein (, online), a region described as a contact with the electron donor, and associate […]

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