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ProTox specifications

Information


Unique identifier OMICS_07760
Name ProTox
Interface Web user interface
Restrictions to use None
Computer skills Basic
Stability Stable
Maintained Yes

Maintainer


  • person_outline Robert Preissner <>

Publications for ProTox

ProTox in publications

 (34)
PMCID: 5886401
PMID: 29621254
DOI: 10.1371/journal.pone.0193565

[…] [–]., il-4 and il-13 tethered exotoxins have already led to clinical trials, e.g., the il-13pe38qqr trial nct00880061 at nih[, ] and the il-4::pseudomonas exotoxin product prx321 in development by protox therapeutics as nct00797940[]. similarly, il-13rα2 as an immunogen is the basis of a dipg/high grade glioma vaccine trial [nct01130077]. this pilot clinical trial evaluated the safety […]

PMCID: 5858232
PMID: 29576712
DOI: 10.4103/pm.pm_62_17

[…] and b (cd28 and cd45) immune cell receptors using maestro 9.3 (schrödinger, llc, cambridge, usa). in addition, top-ranked tested ligands were too explored for toxicity prediction in rodents using protox tool., pyrethroids (specifically type 2) such as fenvalerate (−5.534 kcal/mol: cd8), fluvalinate (−4.644 and − 4.431 kcal/mol: cd4 and cd45), and cypermethrin (−3.535 kcal/mol: cd28) […]

PMCID: 5799276
PMID: 29449808
DOI: 10.3389/fphar.2018.00008

[…] vis-à-vis qualitative structure activity relationship (qsar) and virtual molecular structure activity relationship studies (sars) of the isolated compounds were carried out using swissadme () and protox ()., the molecular targets for the isolated compounds were predicted using mode of action (mod) function of the supernatural ii database (). a total of 10 molecular targets were predicted, […]

PMCID: 5822500
PMID: 29491633
DOI: 10.4103/pm.pm_459_16

[…] of human rsv receptor (pdb: 4ucc) using maestro 9.3 (schrödinger, llc, cambridge, usa). furthermore, kinetic properties and toxicity nature of top graded ligands were analyzed through qikprop and protox tools., notably, rutin (glide score: −8.49), schaftoside (glide score: −8.18) and apigenin-6,8-di-c-β-d-galactoside (glide score − 7.29) have resulted in hopeful natural lead hits […]

PMCID: 5780293
PMID: 29379734
DOI: 10.1016/j.ajur.2017.11.003

[…] saline injection transrectally may be needed., a large randomized trial comparing intraprostatic injection of onabotulinum toxin a 200 u to optimized medical therapy in the treatment of luts/bph (protox study) was done in france, consisting of 127 participants. among the bont group, 73% could interrupt their medical treatment from day 30–120. change in international prostate symptom score […]


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ProTox institution(s)
Structural Bioinformatics Group, Institute for Physiology, Charité - University Medicine Berlin, Berlin, Germany

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