PSDF specifications


Unique identifier OMICS_19211
Alternative name Patient-Specific Data Fusion
Software type Application/Script
Interface Command line interface
Restrictions to use None
Operating system Unix/Linux
Programming languages MATLAB
License GNU General Public License version 3.0
Computer skills Advanced
Version 1.0
Stability Stable
Maintained Yes


No version available


  • person_outline Yinyin Yuan

Publication for Patient-Specific Data Fusion

PSDF citations


Methods for the integration of multi omics data: mathematical aspects

BMC Bioinformatics
PMCID: 4959355
PMID: 26821531
DOI: 10.1186/s12859-015-0857-9

[…] so adopts a mixture modeling approach, using hierarchical Dirichelet process to perform integrative modeling of two datasets. Conversely to MDI, TMD aims at the identification of molecular mechanisms.Patient-Specific Data Fusion (PSDF) [] extends the TMD model for assessing the concordance of biological signals of samples in the two datasets taken into account (CNV and gene expression data). PSDF […]


Approaches to uncovering cancer diagnostic and prognostic molecular signatures

PMCID: 4905187
PMID: 27308330
DOI: 10.4161/23723548.2014.957981

[…] xpression and biclustering on the correlation matrix between mRNA expression and DNA copy number. More sophisticated tools were also developed, such as iCluster and its extended version iClusterPlus, PSDF, MDI, JIVE, and SNF. iCluster is intensely used with TCGA to discover subtypes with distinct clinical outcomes, whereas iClusterPlus is able to handle both discrete (somatic mutations) and contin […]

PSDF institution(s)
Cambridge Research Institute, Cancer Research UK, Cambridge, UK; Department of Oncology, University of Cambridge, Cambridge, UK; Systems Biology Centre, University of Warwick, Coventry, UK
PSDF funding source(s)
Supported by the University of Cambridge, Cancer Research UK and Hutchison Whampoa Limited and an MRC Biostatistics Fellowship.

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