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PSICQUIC specifications


Unique identifier OMICS_02973
Alternative name Proteomics Standard Initiative Common QUery InterfaCe
Interface Web user interface
Restrictions to use None
Computer skills Basic
Stability Stable
Maintained Yes


Publications for Proteomics Standard Initiative Common QUery InterfaCe

PSICQUIC citations


Circulating miRNAs as Putative Biomarkers of Exercise Adaptation in Endurance Horses

Front Physiol
PMCID: 5928201
PMID: 29740341
DOI: 10.3389/fphys.2018.00429

[…] en different lists were identified.The Cytoscape suite (Shannon et al., ) was used to build a protein-protein interaction (PPI) network and the PSIQUIC service ( was used to download proteins interactions from six different public databases (ChEMBL, Spike, GeneMania, mentha, MINT, IntAct). These six networks were merged together in or […]


Novel linear motif filtering protocol reveals the role of the LC8 dynein light chain in the Hippo pathway

PLoS Comput Biol
PMCID: 5746249
PMID: 29240760
DOI: 10.1371/journal.pcbi.1005885

[…] To collect PPIs for LC8 from public databases we applied the PSICQUIC approach []. Known non-linear motif binding partners (DYNLL1, DYNLL2 and UBC) were omitted. To remove redundant hits, the following four filtering steps were applied: 1. For each partner and […]


Proteomics Standards Initiative: Fifteen Years of Progress and Future Work

J Proteome Res
PMCID: 5715286
PMID: 28849660
DOI: 10.1021/acs.jproteome.7b00370

[…] ing a single API (Application Programming Interface). An officially recognized MI-JSON protocol has also been developed for serving MI data to web pages and visualization tools.The need to update the PSICQUIC web service has been discussed as the user community has grown considerably, and there have been issues with the speed of the service experienced by both data suppliers and data users. The po […]


Protein–Protein Interactions in Virus–Host Systems

Front Microbiol
PMCID: 5562681
PMID: 28861068
DOI: 10.3389/fmicb.2017.01557

[…] ve platform was proposed as a solution to integrate all entries, building a single, comprehensive, and non-redundant database. The Proteomics Standard Initiative developed the Common Query Interface (PSICQUIC), a platform to retrieve molecular interaction data from multiple databases storing binary interactions in PSI-MI format (Aranda et al., ).Finally, most of the entries of the aforementioned d […]


Perturbed human sub networks by Fusobacterium nucleatum candidate virulence proteins

PMCID: 5551000
PMID: 28793925
DOI: 10.1186/s40168-017-0307-1

[…] he human interactome that we assembled and used in [, ]. Briefly, protein interaction data were gathered from several databases (e.g., BioGRID, InnateDB, Intact, MatrixDB, MINT, Reactome) through the PSICQUIC query interface [] and from large-scale interaction mapping experiments (e.g., []). We kept only likely direct (i.e., binary) interactions according to the experimental detection method [] an […]


Equine skeletal muscle adaptations to exercise and training: evidence of differential regulation of autophagosomal and mitochondrial components

BMC Genomics
PMCID: 5551008
PMID: 28793853
DOI: 10.1186/s12864-017-4007-9

[…] protein interactions (PPIs) for human, that were annotated to the IMEx (International Molecular Exchange consortium) standard [], were then obtained (12–09-2016) from the IntAct database [] using the PSICQUIC web-service [] (see Additional file for the specific query used). These interactions were recorded across many cell types, tissues and experimental conditions and represent the global set of […]


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PSICQUIC institution(s)
European Molecular Biology Laboratory, European Bioinformatics Institute, Hinxton, UK

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