PTMD specifications


Unique identifier OMICS_32125
Alternative name Post-Translational Modifications Database
Restrictions to use None
Database management system MySQL
Community driven No
Data access File download, Browse
User data submission Not allowed
Version 1.0
Maintained Yes


  • person_outline Yu Xue
  • person_outline Qinghua Cui

Additional information

Publication for Post-Translational Modifications Database

PTMD citation


Characterization of EssB, a protein required for secretion of ESAT 6 like proteins in Staphylococcus aureus

BMC Microbiol
PMCID: 3489787
PMID: 23006124
DOI: 10.1186/1471-2180-12-219

[…] reus membranes in a manner similar to SrtA, a well-characterized membrane embedded protein []. Residues 229–251 roughly define a hydrophobic sequence reminiscent of a transmembrane spanning segment (PTMD). Interestingly, recombinant EssB behaves as a soluble oligomer in E. coli with a rod-shaped like structure and the PTMD sequence appears to be necessary and sufficient for this oligomerization […]

PTMD institution(s)
Department of Bioinformatics & Systems Biology, MOE Key Laboratory of Molecular Biophysics, College of Life Science and Technology and the Collaborative Innovation Center for Biomedical Engineering, Huazhong University of Science and Technology, Wuhan, China; Department of Biomedical Informatics, School of Basic Medical Sciences, MOE Key Laboratory of Molecular Cardiovascular Sciences, Center for Non-coding RNA Medicine, Peking University, Beijing, China
PTMD funding source(s)
Supported by grants from the Special Project on Precision Medicine under the National Key R&D Program of China (Grant Nos. 2017YFC0906600 and 2016YFC0903003), the Natural Science Foundation of China (Grant Nos. 31671360 and 81670462), the Fundamental Research Funds for the Central Universities (Grant No. 2017KFXKJC001), the National Program for Support of Top-Notch Young Professionals, and the program for HUST Academic Frontier Youth Team, China.

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