PTM analysis | Proteomics

PTM analysis steps

Bioinformatics tools

Databases

Tandem mass spectrometry has become a standard tool for identifying post-translational modifications (PTMs) of proteins. Protein modification is an extremely important post-translational regulation that adjusts the physical and chemical properties, conformation, stability and…

PTM analysis | Proteomics

Most Recent Tools

big-Pi…
Web

big-Pi predictor

Evaluates the degree of presence of the C-terminal sequence signal in a query…

Evaluates the degree of presence of the C-terminal sequence signal in a query proprotein sequence based on sequence properties extracted from a learning set. big-Pi predictor allows large-scale…

NetCGlyc
Web
Desktop

NetCGlyc

Produces neural network predictions of C-mannosylation sites in mammalian…

Produces neural network predictions of C-mannosylation sites in mammalian proteins. NetCGlyc correctly predicts 93% of both positive and negative C-mannosylation sites. The method was used to scan…

GlycoDomain…
Web

GlycoDomain Viewer

Enables proteome-wide discovery of O-glycan sites using ‘bottom-up’…

Enables proteome-wide discovery of O-glycan sites using ‘bottom-up’ ETD-based mass spectrometric analysis. GlycoDomain Viewer is a genetic engineering approach that uses human cell lines to…

iSulf-Cys
Web

iSulf-Cys

Predicts the cystein sulfenylation sites in proteins. iSulf-Cys is a predictor…

Predicts the cystein sulfenylation sites in proteins. iSulf-Cys is a predictor which incorporate 14 kinds of physicochemical properties of amino acids. It also showed satisfying performance in the…

Most Popular Tools

SwissPalm
Data

SwissPalm

A comprehensive, manually curated resource to study protein S-palmitoylation.…

A comprehensive, manually curated resource to study protein S-palmitoylation. SwissPalm currently encompasses more than 5000 S-palmitoylated protein hits from seven species, and contains more than…

KinomeXplorer
Desktop

KinomeXplorer

An integrated framework for modeling kinase-substrate interactions and aid in…

An integrated framework for modeling kinase-substrate interactions and aid in the design of inhibitor-based follow-up perturbation experiments.

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