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PyroBayes | An improved base caller for SNP discovery in pyrosequences

A base caller for pyrosequences from the 454 Life Sciences sequencing machines. PyroBayes was designed to assign more accurate base quality estimates to the 454 pyrosequences.

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PyroBayes classification

PyroBayes specifications

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PyroBayes support


  • Aaron Quinlan <>


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Department of Biology, Boston College,Chestnut Hill, MA, USA

Funding source(s)

The US National Human Genome Research Institute (R01 HG003698)

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