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QNB specifications


Unique identifier OMICS_13279
Name QNB
Alternative name Quadratic Negative Binomial
Software type Package/Module
Interface Command line interface
Restrictions to use None
Operating system Mac OS, Windows
Programming languages R
License GNU General Public License version 2.0
Computer skills Advanced
Version 0.99.2
Stability Stable
Source code URL https://cran.r-project.org/src/contrib/Archive/QNB/QNB_1.1.11.tar.gz
Maintained Yes


No version available


  • person_outline QNB Team

Publication for Quadratic Negative Binomial

QNB citations


Binding of N methylscopolamine to the extracellular domain of muscarinic acetylcholine receptors

Sci Rep
PMCID: 5238504
PMID: 28091608
DOI: 10.1038/srep40381

[…] c experiments. Incubations performed at 25 °C were terminated by filtration through Whatman GF/C glass fiber filters in a Brandel filtration apparatus (Sensat, Herts, UK). Non-specific binding of [3H]QNB and [3H]NMS was determined in the presence of 1 μM atropine.The affinity of wild-type and mutated muscarinic receptors for [3H]QNB and [3H]NMS was measured in saturation binding experiments with [ […]


The changing biodiversity of Alabama Drosophila: important impacts of seasonal variation, urbanization, and invasive species

Ecol Evol
PMCID: 5120374
PMID: 27895896
DOI: 10.1002/ece3.2452

[…] ble on species abundance was tested with linear and quadratic models. The final single‐term model was chosen based on the lowest Akaike information criterion (AIC) value. In addition, with linear and quadratic negative binomial GLM models, we tested the influence of the precipitation average in month previous to the collection month on the abundance of mycophagous Drosophila species: D. tripunctat […]


Long Term Activation upon Brief Exposure to Xanomleline Is Unique to M1 and M4 Subtypes of Muscarinic Acetylcholine Receptors

PLoS One
PMCID: 3928307
PMID: 24558448
DOI: 10.1371/journal.pone.0088910

[…] (St. Louis, MO, USA) and xanomeline was from Eli Lilly & Company (Indianapolis, IN, USA). Radiolabeled muscarinic receptor antagonists methyl[3H]scopolamine ([3H]NMS) and quinuclidinylbenzilate ([3H]QNB) were from Amersham (Little Chalfont, Buckinghamshire, UK), radiolabeled adenine was from American Radiolabeled Chemicals (St. Louis, MO). Drugs were diluted directly in Krebs-HEPES buffer unless […]


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QNB institution(s)
Key Laboratory of Information Fusion Technology of Ministry of Education, School of Automation, Northwestern Polytechnical University, Xi’an, China; Department of Electrical and Computation Engineering, University of Texas at San Antonio, San Antonio, TX, USA; Department of Biological Sciences, HRINU, SUERI, Xi’an Jiaotong-Liverpool University, Suzhou, Jiangsu, China; Institute of Integrative Biology, University of Liverpool, Liverpool, UK
QNB funding source(s)
Supported by National Natural Science Foundation of China [No.61473232, No.31671373, No.61401370 and No.91430111]; National Institute on Minority Health and Health Disparities [G12MD007591]; National Institutes of Health [R01GM113245]; Jiangsu University Natural Science Program [16KJB180027]; Jiangsu Science and Technology Program [BK20140403].

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