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Mapping quantitative trait loci (QTL) for complex traits has become a routine tool in functional genomic research. With the advent of highly dense genetic maps of various organisms, a large number of systemic statistical approaches and the corresponding software have been established to dissect the phenotypic variation into several genomic regions, which greatly facilitated the downstream candidate genes discovery and cloning.
(Yang et al., 2008) QTLNetwork: mapping and visualizing genetic architecture of complex traits in experimental populations. Bioinformatics.