bookmark BrainWeb Hosts a Simulated Brain Database (SBD) and allows users to run custom MRI simulations with any of several pulse sequences and source digital phantoms, and arbitrary values of the acquisition artifacts. BrainWeb database contains a set of realistic magnetic resonance imaging (MRI) data volumes produced by an MRI simulator. These data can be used by the neuroimaging community to evaluate the performance of various image analysis methods in a setting where the truth is known. The SBD contains simulated brain MRI data based on two anatomical models: normal and multiple sclerosis (MS). For both of these, full 3-dimensional data volumes have been simulated using three sequences (T1-, T2-, and proton-density- (PD-) weighted) and a variety of slice thicknesses, noise levels, and levels of intensity non-uniformity. These data are available for viewing in three orthogonal views (transversal, sagittal, and coronal), and for downloading.