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SigMol

A specialized repository of quorum sensing signaling molecules (QSSMs) in prokaryotes. SigMol harbors information on QSSMs pertaining to different quorum sensing signaling systems namely acylated homoserine lactones (AHLs), diketopiperazines (DKPs), 4-hydroxy-2-alkylquinolines (HAQs), diffusible signal factors (DSFs), autoinducer-2 (AI-2) and others. Database contains 1382 entries of 182 unique signaling molecules from 215 organisms. It encompasses biological as well as chemical aspects of signaling molecules. Biological information includes genes, preliminary bioassays, identification assays and applications, while chemical detail comprises of IUPAC name, SMILES and structure.

MBPDB / Milk Bioactive Peptide DataBase

Provides an online database of human milk and dairy-derived bioactive peptides. MBPDB is comprehensive for all bioactive milk peptides regardless of species, protein, or function. This online resource contains extensive search functions based on NCBI protein searches that are absent from other databases. MBPDB can be used to search for a specific peptide sequence (singly or a batch of peptidomics data), protein ID, species, function or any combination of these four options.

Quorumpeps

Gives a structured overview of the quorum-sensing (QS) oligopeptides, describing their microbial origin (species), functionality (method, result and receptor), peptide links and chemical characteristics (3D-structure-derived physicochemical properties). The chemical diversity observed within this group of QS signalling molecules can be used to develop new synthetic bio-active compounds. This database can function as a useful tool to justify peptide choices for evaluating different responses or to study quantitative structure–property relationships (QSPRs) of these QS molecules.

QSPpred

A web server for predicting and designing of quorum sensing peptides. QSPpred web server hosts SVM based predictive models i.e. QSPepPred, QSPepDesign and QSPepMap utilizing compositional, binary, physicochemical features and their hybrids. QSPepPred predicts the extent of an input peptide (fasta or multifasta format) as QSP or non-QSP. QSPepDesign can design all possible single position mutants of a given peptide sequence and subsequently predict their QS status. QSPepMap helps to identify potential regions in protein, which may function as QSPs. In addition, it also includes various analysis tools like QSMotifScan, MutGen, PhysicoProp and ProtFrag.