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Performs a graphical visualization of a bait protein interactome derived from a co-immunoprecipitation experiment. RadialTopologyViewer presents the bait as center of the interactome and all interactions identified are positioned in relative proximity to the central bait protein. In contrast to a standard network representation, the length of the edge between the central bait and the interactor can be fixed such that it reflects a property between the bait and the interactor. For example the user can choose to display the likelihood of interaction between the bait and the interactor as a function of the edge length. Moreover, interacting proteins can be grouped together in radial spokes according to a classifier like common GO term.

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RadialTopologyViewer classification

RadialTopologyViewer specifications

Unique identifier:
Graphical user interface
Input data:
A tab delimited flat file with a header, the bait, list of interactors with interaction scores and processes, additional edges between nodes
Operating system:
Computer skills:
Software type:
Restrictions to use:
Output data:
Graphical visualization of the bait protein interactome
Programming languages:

RadialTopologyViewer distribution


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RadialTopologyViewer support


  • John R. Yates <>


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Department of Chemical Physiology, The Scripps Research Institute, La Jolla, CA, USA; Department of Physics, Albert-Ludwigs-University Freiburg, Freiburg, Germany

Funding source(s)

This work was supported by NIH grants 5R01HL079442, P01AG031097, P41 RR011823, DK075295 and HHSN268201000035C, and CFF mass spectrometry fellowship BALCH050X6.

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