ReFOLD specifications


Unique identifier OMICS_17513
Interface Web user interface
Restrictions to use None
Input data A amino acid sequence.
Input format PDB
Computer skills Basic
Version 1.0
Stability Stable
Maintained Yes


  • person_outline Liam J. McGuffin

Publication for ReFOLD

ReFOLD citations


Predictive and Experimental Approaches for Elucidating Protein–Protein Interactions and Quaternary Structures

Int J Mol Sci
PMCID: 5751226
PMID: 29206185
DOI: 10.3390/ijms18122623

[…] he CASP 12 experiment the McGuffin group predicted tertiary structures using IntFOLD [,,,] and other server models, then subsequently the highest scoring submitted model was further refined using the ReFOLD [] procedure. The ReFOLD refinement pipeline consists of three main protocols. The first and second protocol used i3Drefine [] and NAMD [] for structure refinement of the starting model. The ge […]


Protein array identification of protein markers for serodiagnosis of Mycobacterium tuberculosis infection

Sci Rep
PMCID: 4642701
PMID: 26481294
DOI: 10.1038/srep15349

[…] identified as diagnostic protein markers; (4) Correct refolding of the GST fusion proteins: binding of the GST-TB proteins to the GSH-immobilised plates means that all the bound fusion proteins could refold correctly. In addition, the recombinant proteins expressed in E. coli particularly those in inclusion bodies are essential for refolding before their binding to the GSH-immobilized microplates. […]

ReFOLD institution(s)
School of Biological Sciences, University of Reading, Whiteknights, Reading, UK; Lancaster Environment Centre, Lancaster University, UK

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