Tool stats & trends
Looking to identify usage trends or leading experts?
|Alternative name||Roadmap EpiGenome Browser|
|Restrictions to use||None|
|User data submission||Not allowed|
- person_outline Ting Wang
- person_outline Joseph Costello
Publication for Roadmap EpiGenome Browser
Blood triglyceride levels are associated with DNA methylation at the serine metabolism gene PHGDH
[…] obustness to the above novel findings as the cg06500161-triglycerides association had previously been reported, .The cg14476101 site is located in the first intron of the PHGDH gene. According to the Roadmap Epigenome browser, the site is located in the liver in a region enriched for the posttranslational histone modification H3K27Ac (acetylation of lysine 27 of the H3 histone protein) that is ind […]
Bioinformatics Study of Structural Patterns in Plant MicroRNA Precursors
[…] ng in S2 sequences of the required length, miRNA vicinity was annotated in each instance. In lower stem, we distinguished regA region in 5′ strand and regD in the opposite strand. Upper stem included regB region in 5′ strand and regC in 3′ strand ().The first analytical step was done using WebLOGO  and MEME Suite . WebLOGO tool finds the relative frequency of particular nucleotide type at each […]
The RegA regulon exhibits variability in response to altered growth conditions and differs markedly between Rhodobacter species
[…] en on RegA-dependent gene expression. A previous study indicated that loss of RegA had an effect on aerobic expression of cytochrome cbb3 oxidase (), which was unexpected as the cognate sensor kinase RegB that phosphorylates RegA is thought to be active only under anaerobic conditions (; , ; ). When assaying the effect that a loss of RegA had on aerobic gene expression, we observed that 40 genes e […]
An integrative study identifies KCNC2 as a novel predisposing factor for childhood obesity and the risk of diabetes in the South Korean population
[…] owed similar effect in KoCAS-2 but not significant.To evaluate the functional significance of the newly discovered intergenic variant (rs10879834), we analyzed epigenetic regulatory effects using the Roadmap Epigenome Browser, clustering the histone H3K4me1 profile of SNP-harboring regions between ATXN7L3B and KCNC2. Compared with the common enrichment of enhancer marks in ATXN7L3B across cell typ […]
Profiling the reactivity of cyclic C nucleophiles towards electrophilic sulfur in cysteine sulfenic acid† †Electronic supplementary information (ESI) available. See DOI: 10.1039/c5sc02569a Click here for additional data file. Click here for additional data file.
[…] 2 (Prx2; 108 M–1 s–1) and protein tyrosine phosphatase type 1B (PTP1B; 9 M–1 s–1)., Reversible Cys-SOH formation plays a regulatory role among transcription factors, kinases (EGFR, JAK2, Akt2, IKK-β, RegB, PGKase, L-PYK), phosphatases (PTP1B, YopH, PTEN, Cdc25a, SHP-1 and SHP-2), ion channels, peroxidases and cysteine proteases, human serum albumin (HSA) and many other proteins.– Moreover, aberran […]
Integrative analysis of 111 reference human epigenomes
[…] cells, will be of great utility for interpreting genetic changes associated with complex traits. We make all these epigenomic annotations of GWAS regions publicly searchable and browsable through the Roadmap Epigenome Browser and an updated version of the HaploReg database. […]
Looking to check out a full list of citations?
Be the first to review REGB