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RAVEN | In silico detection of sequence variations modifying transcriptional regulation


Searchs putative regulatory genetic variation in favorite gene. SNPs (from dbSNP and user defined) are analyzed for overlap with potential transcription factor binding sites (TFBS) and phylogenetic footprinting using UCSC phastCons scores from multiple alignments of 8 vertebrate genomes.

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RAVEN classification

RAVEN specifications

Unique identifier:
Web user interface
Computer skills:
Regulatory analysis of Variation in ENhancers
Restrictions to use:

RAVEN support


  • Malin C. Andersen <>


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Department of Gene Technology, School of Biotechnology, AlbaNova University Center, Royal Institute of Technology (KTH), Stockholm, Sweden; Atherosclerosis Research Unit, Department of Medicine, Center for Molecular Medicine, Karolinska University Hospital—Solna, Stockholm, Sweden; Computational Biology Unit—Bergen Center for Computational Science and Sars Centre for Marine Molecular Biology, University of Bergen, HIB, Bergen, Norway; Program for Genomics and Bioinformatics, Department of Cell and Molecular Biology, Karolinska Institutet, Stockholm, Sweden; Ontario Cancer Institute, Princess Margaret Hospital, University of Toronto, Toronto, ON, Canada; Centre for Molecular Medicine and Therapeutics (CMMT), Child and Family Research Institute, Department of Medical Genetics, University of British Columbia, Vancouver, BC, Canada; Karolinska Biomics Center, Karolinska University Hospital, Stockholm, Sweden

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