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REMBRANDT specifications


Unique identifier OMICS_29519
Alternative name REpository for Molecular BRAin Neoplasia DaTa

Publication for REpository for Molecular BRAin Neoplasia DaTa

REMBRANDT citations


NFAT1 regulated IL6 signalling contributes to aggressive phenotypes of glioma

PMCID: 5735798
PMID: 29258522
DOI: 10.1186/s12964-017-0210-1

[…] presented as mean ± SEM. The chi-square test, t-test and analysis of variance were used to evaluate the statistical significance among groups. The TCGA glioma dataset and National Cancer Institute’s Repository for Molecular Brain Neoplasia Data (REMBRANDT) database were explored as previously described []. In brief, TCGA and REMBRANDT data were accessed and processed via the GlioVis online platfo […]


Comprehensive protein tyrosine phosphatase mRNA profiling identifies new regulators in the progression of glioma

PMCID: 5009684
PMID: 27586084
DOI: 10.1186/s40478-016-0372-x

[…] REpository for Molecular BRAin Neoplasia DaTa (REMBRANDT) was used to determine Kaplan-Meier curves based on PTP transcript levels (as determined via micro-array analyses) using the online Project Bet […]


Autoregressive Higher Order Hidden Markov Models: Exploiting Local Chromosomal Dependencies in the Analysis of Tumor Expression Profiles

PLoS One
PMCID: 4067306
PMID: 24955771
DOI: 10.1371/journal.pone.0100295

[…] We created a glioma gene expression data set based on data from the Repository for Molecular Brain Neoplasia Data (Rembrandt, current release 1.5.9) containing tumor samples of oligodendrogliomas (WHO grades II and III), astrocytomas (WHO grades II and III) and gliob […]


Molecular Subtypes of Glioblastoma Are Relevant to Lower Grade Glioma

PLoS One
PMCID: 3948818
PMID: 24614622
DOI: 10.1371/journal.pone.0091216

[…] Raw gene expression (Affymetrix U133 Plus 2.0), SNP array (Affymetrix 100K) and clinical data were acquired from the publically available Repository for Molecular Brain Neoplasia Data (Rembrandt) (, which included data on 228 GBMs and 215 GII/IIIs. The histological grade (II vs. III) was avail […]


USP11 regulates PML stability to control Notch induced malignancy in brain tumours

Nat Commun
PMCID: 5645609
PMID: 24487962
DOI: 10.1038/ncomms4214

[…] ed in certain tumours to result in PML degradation. Analysis of the Genevestigator database revealed that USP11 mRNA was abundantly expressed in the brain of normal human tissues (). By searching the Repository for Molecular Brain Neoplasia Data (REMBRANDT) database, which contains microarray-derived gene expression data from patients with malignant glioma, we found that USP11 mRNA was downregulat […]


Modulation of HJURP (Holliday Junction Recognizing Protein) Levels Is Correlated with Glioblastoma Cells Survival

PLoS One
PMCID: 3636219
PMID: 23638004
DOI: 10.1371/journal.pone.0062200
call_split See protocol

[…] The data banks used were: The Cancer Genome Atlas (TCGA), the Repository for Molecular Brain Neoplasia Data (Rembrandt) and NCBI/GEO experiments. Here, the NCBI/GEO dataset refers to the GSE4271 and GSE4412 microarray experiments, which were combined and normali […]


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REMBRANDT institution(s)
National Cancer Institute (NCI), Center for Biomedical Informatics and Information Technology, Bethesda, MD, USA; NCI, Center for Cancer Research, Neuro-Oncology Branch, Bethesda, MD, USA; Science Applications International Corporation (SAIC), VA, USA
REMBRANDT funding source(s)
Supported by the Intramural Research Program of the NIH, National Cancer Institute, Center for Cancer Research and the National Institute of Neurological disorders and Stroke.


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