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Reprever | Resolving low-copy duplicated sequences using template driven assembly

Given paired-end mapped reads and a candidate high-copy region, Reprever identifies (a) the insertion breakpoints where the extra duplicons inserted into the donor genome and (b) the actual sequence of the duplicon. Reprever resolves ambiguous mapping signatures from existing homologs, repetitive elements and sequencing errors to identify breakpoint. At each breakpoint, Reprever reconstructs the inserted sequence using profile hidden Markov model (PHMM)-based guided assembly.

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Reprever classification

Reprever specifications

Unique identifier:
OMICS_01561
Interface:
Command line interface
Operating system:
Unix/Linux
Stability:
Stable
Software type:
Package/Module
Restrictions to use:
None
Computer skills:
Advanced
Maintained:
Yes

Reprever distribution

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No versioning.

Reprever support

Maintainer

  • Sangwoo Kim <>

Credits

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Publications

Institution(s)

Department of Computer Science and Engineering, La Jolla, CA, USA

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