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Rescue site detection software tools | Protein structure analysis

A deleterious amino acid change in a protein can be compensated by a second-site rescue mutation. These compensatory mechanisms can be mimicked by drugs. In particular, the location of rescue mutations can be used to identify protein regions that…
DFS
Desktop

DFS Double Force Scanning

Predicts rescue sites in a protein. DFS can detect candidate rescue sites for…

Predicts rescue sites in a protein. DFS can detect candidate rescue sites for pathogenic mutations using as input only the native structure of a protein. The software focuses on rescue sites that use…

P53 Cancer…
Desktop

P53 Cancer Rescue Project

Predicts positive p53 cancer rescue regions. P53 Cancer Rescue Project is an…

Predicts positive p53 cancer rescue regions. P53 Cancer Rescue Project is an analysis that uses Most Informative Positive (MIP) active learning. MIP was used to select regions in the p53 tumor…

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