ResponseNet statistics

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Citations per year

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Associated diseases

Associated diseases

ResponseNet specifications


Unique identifier OMICS_01562
Name ResponseNet
Interface Web user interface
Restrictions to use None
Computer skills Basic
Version 2.0
Stability Stable
Maintained Yes


  • Plants and Fungi
    • Saccharomyces cerevisiae
  • Primates
    • Homo sapiens


  • person_outline Esti Yeger-Lotem <>

Publications for ResponseNet

ResponseNet in publications

PMCID: 5495484
PMID: 28628618
DOI: 10.1371/journal.pcbi.1005591

[…] where some quantity flows from source nodes, across the edges of a graph, draining in sink nodes. various forms of network flow methodologies have found success in algorithms such as hotnet, responsenet, resistor networks, and others [,,]. diffusion, like the propagation of infection, does not follow algorithmically defined paths on graphs, such as shortest paths, but instead flows […]

PMCID: 5059623
PMID: 27731320
DOI: 10.1038/srep34841

[…] the identification of biomarkers in genome-wide studies and the study of virus-host molecular interactions., examples of network diffusion-based bioinformatics tools include nbs, hotnet, tiedie, responsenet, regmod and stsvm. nbs smooths somatic mutations profiles and then uses network-based non-negative matrix factorisation to stratify subjects. hotnet uses statistics derived from somatic […]

PMCID: 4838525
PMID: 27103885
DOI: 10.5808/GI.2016.14.1.2

[…] network modules or clusters each of which includes a set of the nodes densely connected in the network (). for network clustering or modularization, a number of methods, such as jactivemodules [], responsenet [], netwalker [], and clustermaker [], have been developed (). these methods can be categorized into two groups. one group, such as clustermaker, searches for the node clusters based […]

PMCID: 4357299
PMID: 25814926
DOI: 10.3389/fnmol.2015.00008

[…] and expression of the erad ubiquitin ligase hrd1 suppressed α-synuclein-triggered cytotoxicity (liang et al., ; gitler et al., ). bridging high-throughput genetic and transcriptional data with the responsenet algorithm predicted the aaa-atpase cdc48, also critically involved in erad, to be a modulator of α-synuclein-triggered cytotoxicity (yeger-lotem et al., ). thus, the ups in general, […]

PMCID: 3820512
PMID: 24244133
DOI: 10.1371/journal.pcbi.1003323

[…] developed, and have led to the identification of novel regulators and pathways in several cellular systems , . these include network component analysis (nca) , drem and its recent update sdrem , responsenet and steinernet , . data from time-course gene expression profiles is particularly informative in this context since it can capture chronological events in the cellular system. however, […]

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ResponseNet institution(s)
Department of Clinical Biochemistry and Pharmacology, Ben-Gurion University of the Negev, Beer-Sheva, Israel

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