retrotransposons-spread specifications


Unique identifier OMICS_13019
Name retrotransposons-spread
Software type Package/Module
Interface Command line interface
Restrictions to use None
Operating system Unix/Linux
Programming languages Python
Computer skills Advanced
Stability Stable
Maintained Yes



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  • person_outline Serge Moulin <>

Publication for retrotransposons-spread

retrotransposons-spread in publications

PMCID: 5473901
PMID: 28623259
DOI: 10.1038/s41598-017-02816-8

[…] < 0.05) as compared to untreated cells (fig. ). no significant changes were observed with naked mir34a or blank nanoparticles.figure 4 , long interspersed nuclear elements (line1; l1 elements) are retrotransposons spread across the entire human genome. changes in l1 methylation and l1 genomic activity have also been associated with tumor progression and development–. using bisulfite conversion […]

PMCID: 5341516
PMID: 26902262
DOI: 10.15252/embr.201541866

[…] dna, but represses tf2 transcription with a combination of histone deacetylation, rnai, and physical gene clustering mediated by the fission yeast cenp‐b homologs , , , . like retroviruses, tf2 retrotransposons spread via an rna intermediate and are flanked by long terminal repeats (ltrs), which serve as both promoter and essential untranslated region (utr) . although the exact mechanism […]

PMCID: 3315731
PMID: 22300442
DOI: 10.1186/1423-0127-19-13

[…] may repress gene expression through an epigenetic mechanism. our study strongly supports the observations that young active retrotransposons insert in areas that lack cytosine methylation. retrotransposons spread dna methylation into neighboring regions, generating repressive histone modifications. it causes a significant inactivation of gene expression. hollister et al. reported […]

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retrotransposons-spread institution(s)
Département d’Informatique des Systèmes Complexes, FEMTO-ST Institute, UMR 6174 CNRS, Université de Bourgogne Franche-Comté, Besançon, France; Laboratoire de Mathématiques de Besançon, UMR 6623 CNRS, Université de Bourgogne Franche-Comté, Besançon, France; National Physical Laboratory, Hampton Road, Teddington, UK; Laboratoire Biometrie et Biologie Evolutive, Universite Claude Bernard - Lyon 1, UMR 5558 CNRS, Villeurbanne, France
retrotransposons-spread funding source(s)
This work has been supported by the Transposable Elements project of the Franche-Comté region. The work of S.C. was also sponsored by NMS/IRD project.

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